Since 2006, We, Beijing Zhongshuo Pharmaceutical Technology Development Co.,Ltd began to focus on the research, manufacturing and export of Entecavir API & Intermediates. We are one of the biggest producer of Etv. In China. The assay of its API is over 99.96%, the assay of single impurity is even less 0.01%, which can match up to SFDA standard on drug-importing registration. The production of Etv. API per month is about 1000 grams. The assay of its intermediate is above 98%, which production per month is about 1kg. In addition ,we have different manufactory process for Entecavir API from the original company, BMS.

CERTIFICATE OF ANALYSIS is as follows:
Name: Entecavir Monohydrate
CAS number: 209216-23-9
Appearance: White or off-white crystalline powder
Identification: H-1 NMR spectrum
Single Impurity:0.01%
Water: 6.2%
Assay (HPLC) : 99.97 %

And Etv. Intermediates are supplied all year round.
N-1
3-Cyclopenten-1-o1,2-[(phenylmethoxy)methyl]-(1R-trans)
C13H16O2
CAS No:188399-48-6
HPLC Assay:98%

N-2
(1S,2R,3S,5R-2-(benzyloxymethyl)-6-oxabicyclo[3.1.0]hexan-3-ol
C13H16O3
CAS No: 117641-39-1
HPLC Assay:98%

N-3
6-Oxabicyclo[3.1.0]hexane,3-(phenylmethoxy)-2-
[(phenylmethoxy)methyl]-,(1S,2R,3S,5R)
C20H22O3
CAS No:110567-22-1
HPLC Assay:98%

N-4
1S,2R,3S,5S-5-(2-amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
C32H33N5O4
CAS No: 142217-77-4
HPLC Assay:99%

N-8
6-(benzyloxy)-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-
Methylenecyclopentyl]-9H-purin-2-amine
C33H33N5O3
CAS No:204845-95-4
HPLC Assay: 99%

Normally we have 10g Entecavir API and 100g Entecavir API Intermediates in stock. In addition ,we have different manufactory process for Entecavir API from the original company, BMS. While the most important is that our product has the absolute price advantage.

Hope we can make some cooperations in the near future.

Optional Information
- HS Code : 3006 Pharmaceutical Goods