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Purity: 99
Model Number: 1197-18-8
Brand Name: NJBN STEROID
Grade Standard: Medicine Grade
Type: Immune Function Agents
Place of Origin: China (Mainland)
EINECS No.: NJBN STEROID
MF: C8H15NO2
Other Names: Amstat
CAS No.: 1197-18-8
Sample: Free
Market: Worldwide

Specifications

Amstat 1197-18-8 For Prevent Excessive Blood Loss

Product Name: Amstat

Synonyms: TIMTEC-BB SBB006715;TRANS-4-AMINOMETHYL-1-CYCLOHEXANECARBOXYLIC ACID;trans-4-aminomethylcyclohexane-1-carboxylate;TRANS-4-(AMINOMETHYL)CYCLOHEXANECARBOXYLIC ACID;TRANEXAMIC ACID;amstat;amcha;amikapron
CAS: 1197-18-8
MF: C8H15NO2
MW: 157.21
EINECS: cChemical Properties white crystalline powder
Usage Antifibrinolytic agent; blocks lysine binding sites of plasminogen. Hemostatic.
Usage Used as a lysine analogue to characterize binding sites in plasminogen.1,2

 
COA

Items of analysis

Specification

Results

Appearance

White crystalline powder

White crystalline powder

Solubility

Soluble in water and glacial acetic acid, almost not soluble in ethanol and acetone (96%)

Soluble in water and glacial acetic acid, almost not soluble in ethanol and acetone (96%)

Identification

Infrared absorption map complies with the tranexamic acid comparison map

Infrared absorption map complies with the tranexamic acid comparison map

PH

7.0~8.0

7.25

Loss on drying

≤0.5%

0.06%

Residue on ignition

≤0.1%

0.01%

Heavy metals

≤10ppm

<10ppm

Sulphate ash

≤0.1%

<0.07%

Chloride

≤140ppm

<140ppm

Arsenic

≤2ppm

<2ppm

Related substances

A≤0.1%, B≤0.2%, C≤0.1%, D≤0.1%

A=0.031%, B=0.0812% , C=0.0095%, D=0.0066%

Total impurities

(except A,B) ≤0.2% 

Total impurities(except A,B)=0.015%

Assay

99.0%~101.0%

99.8%

Conclusion

Qualified



Description:Tranexamic acid is a medication used to treat or prevent excessive blood loss from trauma, surgery, and in various medical conditions including hemophilia and heavy menstrual bleeding. It comes in oral and intravenous forms.

Side effects are uncommon and include gastrointestinal effects, dizziness, fatigue, headache, and hypersensitivity reactions.The medication needs to be used cautiously in people with kidney disease and who are at a high risk for blood clots. Tranexamic is safe to use in pregnant women. However, caution should be used in lactating women.[1] It is an antifibrinolytic.

It was discovered in 1962 by Utako Okamoto and has been on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

Amstat 1197188 For Prevent Excessive Blood Loss