1-Adamantanamine hydrochloride 665-66-7 For Antiviral And Antiparkinsonian

Product Name: 1-Adamantanamine hydrochloride
Synonyms: TIMTEC-BB SBB003680;TRICYCLODECANE HYDROCHLORIDE;1-ADAMANTYLAMINE HYDROCHLORIDE;1-ADAMANTANAMINE HCL;1-ADAMANTANAMINE HYDROCHLORIDE;1-ADAMANTANEAMMONIUM CHLORIDE;1-AMINOADAMANTANE HYDROCHLORIDE;ADAMANTAN-1-AMINE HYDROCHLORIDE
CAS: 665-66-7
MF: C10H18ClN
MW: 187.71
EINECS: 211-560-2
Chemical Properties Crystalline Solid
Usage antiviral, antiparkinsonian; treatment of drug-induced extrapyrimidal reactions

 

Items of analysis	Specification	Results
Appearance	White or light yellow crystalline powder	White crystalline powder
Identification(IR)	Positive	Positive
Assay(titration)	99.0%~101.0%	99.86%
Clarity and color of solution (2 g in 10 ml water)	clear and nearly colorless	conform
PH	3.0~5.5	3.92
Heavy metals	≤0.001%	0.0004%
Loss on drying	≤0.5%	≤0.23%
Individual impurities	≤0.3 %	0.26%
Total impurities	≤1.0%	0.44%
Conclusion	Qualified

Description :Amantadine (trade name Symmetrel, by Endo Pharmaceuticals) is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an antiparkinsonian drug. It is the organic compound 1-adamantylamine or 1-aminoadamantane, meaning it consists of an adamantane backbone that has an amino group substituted at one of the four methyne positions. Rimantadine is a closely related derivative of adamantane with similar biological properties.

Apart from medical uses, this compound is useful as a building block in organic synthesis, allowing the insertion of an adamantyl group.