High purity Ribavirin 36791-04-5 for Antiviral Agent


Product Name: Ribavirin 
Synonyms: REBETOL;RIBAVIRIN;rtca;tribavirin;vilona;VIRAMID;VIRAZID;VIRAZOLE 
CAS: 36791-04-5 
MF: C8H12N4O5 
MW: 244.2 
Chemical Properties Colourless Solid 
Usage Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent. 

COA

Items of analysis	Specification	Results
Appearance	Should be white crystalline powder; no smell, tasteless	White crystalline powder
Specific rotation	－35.0°～ -37.0°	-36.4°
Chemical reaction	Should be a positive response	Positive reaction
Liquid chromatography	the sample peak retention time and the comparison should be consistent peak	Consistent with the peak of the control
Infrared spectrum	the infrared spectrum of the test sample should be consistent with the control.	Consistent with the control
pH	4.0～6.5	4.8
Solution clarity	Should comply with the provisions	Conform
Loss on drying	0.5%	0.29%
Residue on ignition	0.1%	0.09%
Heavy metals	0.001%	Conform
Singleimpurity	0.25%	0.03%
Total impurity	1.0%	0.06%
Microbial limit	Should comply with the provisions	Conform
Assay	98.5～101.5%	99.5%
Conclusion	Qualified

Description:

Ribavirin, also known as tribavirin, is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. for hepatitis C it is used with other medications such as simeprevir, sofosbuvir, peginterferon alfa-2b or peginterferon alfa-2a. among the viral hemorrhagic fevers it is used for Lassa fever, Crimean–Congo hemorrhagic fever, and Hantavirus infection but not Ebola or Marburg. Ribavirin is take by mouth or inhaled.

Ribavirin approved for medical use in 1986. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. It is avaliable as a generic medication.