St. John's wort 1 Descriptions and Specifications of Product Content Specifications: 0.3% Hypericin by UV 3.0% Hyperforin by HPLC 2 St. John's wort (Hypericum perforatum in Latin) is a long-living plant with yellow flowers which belongs to the family of Guttiferae. St. John's wort is native to Europe, West Asia, North Africa, Madeira and the Azores, and is naturalized in many parts of the world, notably North America and Australia. 2.1 Hypericin Molecular Formula: C30H16O8 Molecular Mass: 504.443 CAS NO: 548-04-9 Constitutional Formula: 2.2 Hyperforin Content Specifications: 3% by HPLC Molecular Formula: C35H52O4 Molecular Mass: 536.785 CAS NO: 11079-53-1 Constitutional Formula: 3. Indications and Uses St. John's wort has been used for centuries to treat mental disorders and nerve pain. In ancient times, herbalists wrote about its use as a sedative and a treatment for malaria, as well as a balm for wounds, burns, and insect bites. Today, St. John's wort is used by some for depression, anxiety, and/or sleep disorders.