The medical benefits of gingko biloba extract (GBE) rely on the proper balance of
two groups of active components; the gingko flavone glycosides and the terpene
lactones. The 24% ginkgo flavone glycoside designation on GBE labels indicates
the carefully measured balance of bioflavonoids. These bioflavonoids are primarily
responsible for GBE's antioxidant activity and ability to inhibit platelet aggregation
(stickiness). These two actions may help GBE prevent circulatory diseases, such as
atherosclerosis and support the brain and central nervous system. The unique terpene
lactone components found in GBE, known as ginkgolides and bilobalide, increase
circulation to the brain and other parts of the body as well as exert a protective effect
on nerve cells. Ginkgolides may improve circulation and inhibit platelet-activating factor (PAF). Bilobalide protects the cells of the nervous system. Recent
animal studies indicate that bilobalide may help regenerate damaged nerve cells.