Microcrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles.
It is commercially available in different particle sizes and moisture grades that have different properties and applications.
Product name: Microcrystalline cellulose 101/102
Synonyms:cellulose gel; crystalline cellulose; Fibrocel; Tabulose;
Chemical Name: Cellulose
CAS No:9004-34-6
Molecular Formula:(C6H10O5)n ,where n ≈ 220.
Molecular Weight:≈36 000
Functional Category: Adsorbent; suspending agent; tablet and capsule diluent; tablet disintegrant.
Specifications: Pharmaceutical grade
|
Test item |
Pharmaceutical |
|
Appearance |
White fine powder |
|
Identification A |
Pass |
|
Identification B(Degree of Polymerization) |
≤300 |
|
Conductivity |
＜75 μs/cm |
|
Moisture % |
3.0-5.0 |
|
PH |
5.0-7.5 |
|
Loss on drying max |
7.0% |
|
Bulk density |
0.26-0.34 |
|
Water-soluble substances max |
0.24% |
|
Heavy metal max |
0.001% |
|
Ether-soluble substances |
0.05% |
|
Residue on ignition max |
0.05% |
|
Total aerobic microbial count |
<100cfu per g |
|
Molds and yeasts count |
<10cfu per g |
|
S.Aureus /10g |
Absent |
|
Salmonella species /10g |
Absent |
|
E. Coli /10 g |
Absent |
|
P.Aeruginosa/10g |
Absent |
Applications:
Microcrystalline cellulose is widely used in pharmaceuticals, primarily as a binder/diluent in oral tablet and capsule formulations where it is used in both wet-granulation and direct-compression processes. In addition to its use as a binder/diluent, microcrystalline cellulose also has some lubricant and disintegrant properties that make it useful in tableting.
Microcrystalline cellulose is also used in cosmetics and food products.
Package:15kg/bag
Period of validity:2 years