PVP/VA is a kind of water-solubility macromolecule resin, white powder or transparent liquor, no smell, not absorption of moisture, can dissolve in water-ethanol and anhydrous alcohols, has good cohesiveness, hygroscopic, film forming and surface activity character.
Product name : PVP VA64
CAS No. : 25086-89-9
Molecular formular: (C6H9ON)n×(C4H6O2)m (n=1. 2m)
Molecular weight:
Chemcial name: Vinylpyrrolidone and vinyl acetate copolymer, Copovidone
Key words: Copovidone, Copovidonum
Chemical Structure:
Specification: pharmaceutical grade
Product |
Pharm grade |
Appearance |
White or creamy white, free-flowing power |
Aldehyde ppm max |
500 |
Peroxide ppm max |
400 |
Hydrazine ppm max |
1 |
Monomers %max |
0. 1 |
2-Pyrrolidone %max |
0. 5 |
Heavy metal ppm max |
20 |
Moisture % max |
5 |
Sulphate ash % max |
0. 1 |
K value |
25. 2-30. 8 |
VA content % |
35. 3-42 |
Nitrogen content % |
7. 0-8. 0 |
Application:
It possesses excellent adhesiveness, flexibility, forms a hard film and other characters, mainly used as a water-soluble binder and dry binder when used in wet granulation and direct compression tablet processes, also used as a film-forming material in film coatings.
a. Binding agent: used in wet granulation processes.
b. Dry binding agent: used in direct compression tablet processes.
c. Film coating agent: used for film promoters and sugar coating to prevent splitting, bottom binder to prevent moisture sensitivity.
d. Crazing agent: acts in taste preparating and coating films.
Storage: should be preserved in tight container.
Packaging: 10 kg / drum
Period of validity: 2 years