Original plant: Is the dried flower bud or opening flower of Lonicera japonica Thunb., Lonicera hypoglauca Miq., Lonicera confusa DC. Or Lonicera dasystyla Rehd. (Fam. Caprifoliaceae).

Specification: 4%-99%

Chemical Name: 3-O-caffeoylquinic acid Test Method: HPLC Molecular formula: C16H18O9 Molecular weight: 354. 31 CAS No. : 327-97-9 EINECS No. : 206-325-6 Melting Point: 205-209°C

Solubility: Good solubility in water, easy soluble in hot water, ethanol, acetone, hard soluble in ethyl acetate.

Pharmacology Action: Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major phenolic compound in coffee, but is also found widespread in plants and can be isolated from the leaves and fruit This compound, long known as an antioxidant, also slows the release of glucose into the bloodstream after a meal.

This acid is an important factor in plant metabolism. It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters; at concentrations as high as 100 μg/L, does not inhibit the 5-lipoxygenase activity of ionophore-stimulated human polymorphonuclear leukocytes. Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to the prevention of Type 2 Diabetes Mellitus and cardiovascular disease .

Chlorogenic acid is an important factor in plant metabolism. It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters. Chlorogenic acid, at concentrations as high as 100 um, does not inhibit the 5-lipoxygenase activity of ionophore-stimulated human polymorphonuclear leukocytes.