Methl folate CAS NO. 134-35-0 SYNONYMS L-5-Methyltetrahydrofolic acid, calcium salt L-Methyltetrahydrofolate, calcium salt L-Methylfolate, calcium L-5-MTHF-Ca DEFINITION Calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca) is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate. It is synthesized by reduction of folic acid to tetrahydrofolic acid followed by methylation and diastereoselective crystallization (in water) of L-5-MTHF as its calcium salt. The product contains variable amounts of water of crystallization. Chemical name N-{4-[[((6S)-2-amino-3, 4, 5, 6, 7, 8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl}-L-glutamic acid, calcium salt C. A. S. Number 151533-22-1 Chemical formula C20H23CaN7O6 (anhydrous form)