M.Wt: 447.88 C23H23ClFNO5
Storage at -20C 2 years
Solubility: Unknown
Cas number: [697761-98-1]
Elvitegravir, a quinolone carboxylic acid strand-transfer specific inhibitor that displayed an IC50 of 7 nM against IN and antiviral EC90 of 1.7 nM in the presence of NHS. In pharmacokinetics, in rat and dog elvitegravir displayed a 34% and 30% bioavailability, a 2.3 h and 5.2 h half-life,and a 8.3 mL/min/kg and 17 mL/min/kg clearance, respectively.
Erik Serrao, Srinivas Odde, et al.Retrovirology 2009, 6:25. Kearney B, Mathias A, Zhong L. International Workshop on Clinical Pharmacology of HIV Therapy. Lisbon 2006
Storage at -20C 2 years
Solubility: Unknown
Cas number: [697761-98-1]
Elvitegravir, a quinolone carboxylic acid strand-transfer specific inhibitor that displayed an IC50 of 7 nM against IN and antiviral EC90 of 1.7 nM in the presence of NHS. In pharmacokinetics, in rat and dog elvitegravir displayed a 34% and 30% bioavailability, a 2.3 h and 5.2 h half-life,and a 8.3 mL/min/kg and 17 mL/min/kg clearance, respectively.
Erik Serrao, Srinivas Odde, et al.Retrovirology 2009, 6:25. Kearney B, Mathias A, Zhong L. International Workshop on Clinical Pharmacology of HIV Therapy. Lisbon 2006