Name Fludarabine
Synonyms 9-bata-D-Arabinofuranosyl-2-fluoroadenine; 2-Fluoroadenine-9-bata-D-arabinofuranoside
Molecular Formula C10H12FN5O4
Molecular Weight 285.23
CAS Registry Number 21679-14-1
EINECS 244-525-5
Use: Anticancer
Appearance: White powder
Function: Fludarabine is highly effective in the treatment of chronic lymphocytic leukemia, producing higher response rates than alkylatine agents such as chlorambucil alone. Fludarabine is used in various combinations with cyclophosphamide, mitoxantrone, dexamethasone and ribuximab in the treatment of indolent non-Hodgkins lymphomas. As part of the FLAG regimen, fludarabine is used together with cytarbine and granulocyte colony-stimulating factor in the treatment of acute myeloid leukaemia. Because of its immunosuppressive effects, fludarabine is also used in some conditioning regimens prior to non myeloablative allogeneic stem sell transplant..
Specification: >99%