HA has peculiar physical and chemical property and biologic action, widely used in medicine. It can be used as a viscoelastic agent in artificial crystal planting in ocular surgery, as a fill agent in osteoarthritis, also as an agent in eye drops. It has good action of adhesion preventives in surgerical operations and healing cuts on skin. Compound of HA and other drug, the additive can make the action of drug delaying. With the development of medical technology. HA will be more widely used in medicine