Genistein
Melting point: 297~298℃
Solubility: Soluble in DMSO and Ethanol,hardly dissolve in water.
Pharmacology Action: Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.
Original Plant: Seed of Sophora japonica L.
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Synonyms: CI 75610; Genestein; genisteol; genisterin; prunetol; sophoricol
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Chemical Name: 4',5,7-trihydroxyisoflavone 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
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Specification: 98%
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Test Method: HPLC
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Molecular Formula: C15H10O5
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Molecular Weight: 270.23
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CAS No.: 529-59-9
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Solubility: Soluble in DMSO and Ethanol,hardly dissolve in water.
Pharmacology Action: Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.
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