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Genistein
Original Plant: Seed of Sophora japonica L.
Synonyms:  CI 75610; Genestein; genisteol; genisterin; prunetol; sophoricol
Chemical Name: 4',5,7-trihydroxyisoflavone 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Specification:  98%
Test Method:  HPLC
Molecular Formula:  C15H10O5
Molecular Weight:  270.23
CAS No.:  529-59-9
Melting point:  297~298℃
Solubility:  Soluble in DMSO and Ethanol,hardly dissolve in water.
Pharmacology Action: Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities.

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