Synonym Names for TMPO peptide: TMPO; LAP2; Thymopoietin isoform alpha; TP alpha; Thymopoietin-related peptide isoform alpha; TPRP isoform alpha; Lamina-associated polypeptide 2, isoform alpha

Thymopentin. also known as TP-5. is a thymopoietin pentapeptide. and it is a synthesized derivative of thymopoietin. a naturally occurring hormone responsible for inducing T-cell precursors to differentiate and mature.

Function: May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Play an important role, together with LMNA, in the nuclear anchorage of RB1.

Function: TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide.

Subunit: Interacts with LMNA, BANF1 and RB1 and with chromosomes. Associates directly or indirectly with lamins at specific cell-cycle stages.

Subcellular Location: Nucleus. Note=Expressed diffusely throughout the nucleus.

Tissue Specificity: Expressed in many tissues. Most abundant in adult thymus and fetal liver.