Crystallization condition screening
  Co-crystallization and soaking
3-D structural determination 
  Structural-Based Drug Design (SBDD)
 Target family analysis: using prior knowledge (specificity)
Homology modelin
Quantitative structure-activity relationship (QSAR)
 Virtual drug screening
Pharmacophore match for docking-based virtual screen Hypothesis-driven docking
 Enhancing results of virtual screens using data mining
•          De novo drug design