1. Antioxidant: Sesamin helps protect blood vessels by scavenging free radicals and ensuring efficient nutrient and oxygen delivery for healthy brain function.
2. Bactericide
3. Insecticide
4. Decreasing fat storage 
5. Antihypertensive: Sesamin induces nitric oxide and decreases endothelin-1 production in HUVECs, possible implications for its antihypertensive effect.
6. Provide liver protection against alcohol and improve liver function:Sesamin is a non-competitive inhibitor of Δ5-desaturase, It inhibits the conversion of DGLA to arachidonic acid, and consequently decreases the formation of proinflammatory 2-series prostaglandins.
7. Decrease cholesterol levels, while increasing high density lipoprotein (HDL aka "good cholesterol") levels
8. Be an anti-inflammatory
9.  Skin problem: The experiments in rats shows that sesamin can inhibit the growth of SC (skin cancer) cell. It can protect skin from UV rays.