Teicoplanin; CAS No:61036-62-2 

Additional Names: teichomycin A2

Molecular formula: Teicoplanin A2-2, C88H97Cl2N9O33

Molecular Weight:  1879.68

Application

Teicoplanin is a glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria. It acts against both methicillin sensitive and methicillin resistant Staphylococcus aureus (S. aureus). It is as efficacious as vancomycin against these organisms. The efficacy of teicoplanin against Staphylococcus aureus can be improved by addition of aminoglycosides for synergistic effect. Teicoplanin is more efficacious than vancomycin for some of the streptococci especially enterococci. Teicoplanin is also effective against Listeria monocytogenes, Corynebacterium spp., Clostridium spp., and anaerobic Gram-positive cocci(2).

Specification  JP

Appearance: A white to light yellowish white powder.

Assay(potency): Not less than 900ug(potency) per mg calculated on the anhydrous de-sodium chloride and de-residual solvents basis.

Active component:

1.       TA2 group: ≥80.0%

2.       TA3group: ≤15.0%

3.       Other group: ≤5.0%

Sodium chloride: ≤5.0%

Ph(0.5g/10ml): 6.3~7.7