Additional Names: 4-carbamoyl-1-b-D-ribofuranosylimidazolium-5-olate

Molecular Formula:  C9H13N3O6

Molecular Weight:  259.22

Application

A new immunosuppressive drug. The strong immunosuppressive activity of mizoribine was already demonstrated in various animal models, in renal transplantation and in steriod-resistant nephrotic syndrome. Recently, the remarkable clinical advantages of an imidazole for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases were reported.

Specification: JP

Appearance: white to off-white crystalline powder

Related substances: ≤1.5%

Assay(on the dry basis): 98%~102%

Optical rotation:[α]20D –25—27°

Heavy metals: ≤20ppm

Water: ≤0.5%

Residue on ignition: ≤0.1%