1.Brinzolamide /cas no .138890-62-7
2. Carbonic anhydrase inhibitor used to lower intraocular pressure
3.Sincerely supplier
2. Carbonic anhydrase inhibitor used to lower intraocular pressure
3.Sincerely supplier
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ITEMS
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STANDARD
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RESULT
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APPEARANCE
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White to yellow powder
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White powder
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Identification
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A.Should meet the requirement
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Conforms
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B. Should meet the requirement
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Conforms
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Impurity A
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≤0.5%
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0.18%
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Impurity B
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≤0.3%
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0.10%
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Total impurity
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≤1.0%
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0.80%
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Loss on drying
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≤0.5%
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0.12%
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Residue on lgnition
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≤0.1%
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0.085%
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Residual solvent
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Ethanol≤0.5%
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0.065%
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Ethyl acetate≤0.5%
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N.D.
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Tetrahydrofuran ≤0.072%
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N.D.
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Heavy metal
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≤20ppm
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Conforms
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Assay
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98.0%~102.0%
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99.32%
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Conclusion
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Conforms to the requirement of USP32.
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