English name: Resveratrol English alias: 3, 4 ', 5-Trihydroxy-trans-stilbene; 5-[(1 E)-2-(4-Hydroxyphenyl) ethenyl]-1, 3-benzenediol CAS number: 501-36-0 molecular formula: C14H12O3 molecular weight: 228.24 MDL number: MFCD00133799 physical and chemical properties: colorless needle crystal, easily soluble in ethyl ether, chloroform, methanol, ethanol, acetone, etc Microherb from trans resveratrol
Editor this period of physical properties
Resveratrol tasteless, white crystal (methanol); Soluble in water, soluble in ethanol, acetone, etc. Melting point of 253-255 ℃, 261 ℃ is sublimation.
Editor this period of stability
This product under uv irradiation can produce fluorescence, pH > 10, stability is poorer, meet chloride-ferric chloride-iron QingHuaJia solution is blue, encounter such as ammonia alkaline solution to appear red. Resveratrol light is not stable, Microherb stability test shows, high purity resveratrol ethanol solution in avoid light conditions also can only stable for days, because this proposal resveratrol content analysis suggest reference substance solutions and a sample solution with the match with use.
Edit this paragraph isomers
Resveratrol in natural conditions with free state and glycosidase-catalysed two forms exist, resveratrol) and chemical structure is the type and respectively in trans two isomers, namely the cis-regulatory resveratrol (cis-Res), trans resveratrol (trans-Res) and the type of resveratrol PD (cis-PD), trans resveratrol PD (trans-PD). After two forms on the enzyme action) under release resveratrol, plant of resveratrol mainly trans form existence, research shows that trans isomers physiological activity of the type is better than oil.
Editor this period of plant origin
In 1940 for the first time found that resveratrol, were discovered in 1970 s in grapes contains this kind of material, the people later found tiger rod, peanut, mulberry and other plant also contains this kind of composition. Natural pectase alcohol is a kind of natural active ingredient, it can be pretreated with (the type, trans) and glycosidase-catalysed combination state (the type, trans) two forms in plants (such as traditional Chinese medicine material tiger rod) distribution and synthetic biology, and all have antioxidant effectiveness, of which the isomers of trans biological activity is better than the type, is a kind of important of grape plant antitoxin. It is about its natural resources through an extensive research, at least in the 21 families, 31 of the genera of 72 kinds of plants discovered resveratrol, such as: the grape vine families of snake of Portugal, also, the peanuts, JueMing of legume of tree, of the lily family LiLu genera, myrtle families of eucalyptus, polygonaceae's (fagopyrum esculentum), etc. Contain resveratrol is common many of the plants of medicinal plants, such as JueMing, LiLu, tiger and his staff, some is food, such as: grapes. Grape skins of the highest content of resveratrol, can be up to 50 to 100 mg/kg. In 1992, for the first time in the wine business that resveratrol. Foreign numerous studies have demonstrated that resveratrol is the wine (especially the red wine) the effect of the most important ingredients. However, not all of the red wine all has this kind of composition, blending wine and inferior wine is not out of the measure. Because resveratrol is to resist invasion vines mold produce a kind of plant antitoxin, produce in grape skin after kept. According to the traditional way only with the skin of the brewing wine, grapes skin of resveratrol will be brewing in the process was gradually produce alcohol dissolve. Like a think trans resveratrol is red wine can atherosclerosis and coronary heart disease resistance of the important component. Therefore, resveratrol content in wine to determine the level of the wine of the intensity of healthy effects. Different grape varieties of resveratrol content difference is very big. According to YuanYiXi Cornell university professor clay west Ph.D. (Dr. Leory Creasy) research, the origin of the French wave gen area of the pinot noir grape, contains the highest concentration of resveratrol. Origin of bordeaux merlot and cabernet sauvignon, also has quite high content. In addition to grape variety, in addition to the content of resveratrol, is the grapevine. In cold and wet area of planting pinot noir, especially in the harvest season cold wet area, because the conditions conducive to infect mold, pinot noir of the vines will produce more of the resveratrol to safeguard the health of the self. According to dr west of clay, from the division of the lake's Finn pinot noir wine, has one of the highest resveratrol content, even more than the original production of pinot noir French wave gen similar wine of some times. In the 1980 s, the world health organization survey found that although the French high fat food preference cheese, but tiger rod
Coronary heart disease incidence and mortality rates lower than other western countries, it may be caused by and the French often drink wine containing resveratrol relevant. Since then, concern about resveratrol. So far at least 21 families, 31, has been in 72 kinds of plants are found resveratrol. Resveratrol mainly comes from Polygonaceae Polygonaceae plant tiger Polygonum cuspidatum Sieb rod. Et Zucc. Dry roots and root, grapes, Vitis vinifera fruit plants grape skins and seeds, leguminosae Fabaceae plants the seeds of peanut Arachis hypogaea etc.
Editor this section analysis method
Using C18 column to acetonitrile: water (volume than bonds wherewith 0) solution as mobile phase, using ultraviolet detector in 306 nm place detection. The results showed that the concentration of resveratrol in 10 to 250 μ g/mL, concentration and peak area is good linear relationship between (r = 0.9999); The labeled recovery is 9.25% ~ 10.26%; Minimum detection concentration 0.6 mg/g. Production can adjust the flow velocity and the tiger (and the rod resveratrol enzyme solution transformation.
Edit this paragraph that USES
COX as he 1 selective inhibition
Resveratrol tasteless, white crystal (methanol); Soluble in water, soluble in ethanol, acetone, etc. Melting point of 253-255 ℃, 261 ℃ is sublimation.
Editor this period of stability
This product under uv irradiation can produce fluorescence, pH > 10, stability is poorer, meet chloride-ferric chloride-iron QingHuaJia solution is blue, encounter such as ammonia alkaline solution to appear red. Resveratrol light is not stable, Microherb stability test shows, high purity resveratrol ethanol solution in avoid light conditions also can only stable for days, because this proposal resveratrol content analysis suggest reference substance solutions and a sample solution with the match with use.
Edit this paragraph isomers
Resveratrol in natural conditions with free state and glycosidase-catalysed two forms exist, resveratrol) and chemical structure is the type and respectively in trans two isomers, namely the cis-regulatory resveratrol (cis-Res), trans resveratrol (trans-Res) and the type of resveratrol PD (cis-PD), trans resveratrol PD (trans-PD). After two forms on the enzyme action) under release resveratrol, plant of resveratrol mainly trans form existence, research shows that trans isomers physiological activity of the type is better than oil.
Editor this period of plant origin
In 1940 for the first time found that resveratrol, were discovered in 1970 s in grapes contains this kind of material, the people later found tiger rod, peanut, mulberry and other plant also contains this kind of composition. Natural pectase alcohol is a kind of natural active ingredient, it can be pretreated with (the type, trans) and glycosidase-catalysed combination state (the type, trans) two forms in plants (such as traditional Chinese medicine material tiger rod) distribution and synthetic biology, and all have antioxidant effectiveness, of which the isomers of trans biological activity is better than the type, is a kind of important of grape plant antitoxin. It is about its natural resources through an extensive research, at least in the 21 families, 31 of the genera of 72 kinds of plants discovered resveratrol, such as: the grape vine families of snake of Portugal, also, the peanuts, JueMing of legume of tree, of the lily family LiLu genera, myrtle families of eucalyptus, polygonaceae's (fagopyrum esculentum), etc. Contain resveratrol is common many of the plants of medicinal plants, such as JueMing, LiLu, tiger and his staff, some is food, such as: grapes. Grape skins of the highest content of resveratrol, can be up to 50 to 100 mg/kg. In 1992, for the first time in the wine business that resveratrol. Foreign numerous studies have demonstrated that resveratrol is the wine (especially the red wine) the effect of the most important ingredients. However, not all of the red wine all has this kind of composition, blending wine and inferior wine is not out of the measure. Because resveratrol is to resist invasion vines mold produce a kind of plant antitoxin, produce in grape skin after kept. According to the traditional way only with the skin of the brewing wine, grapes skin of resveratrol will be brewing in the process was gradually produce alcohol dissolve. Like a think trans resveratrol is red wine can atherosclerosis and coronary heart disease resistance of the important component. Therefore, resveratrol content in wine to determine the level of the wine of the intensity of healthy effects. Different grape varieties of resveratrol content difference is very big. According to YuanYiXi Cornell university professor clay west Ph.D. (Dr. Leory Creasy) research, the origin of the French wave gen area of the pinot noir grape, contains the highest concentration of resveratrol. Origin of bordeaux merlot and cabernet sauvignon, also has quite high content. In addition to grape variety, in addition to the content of resveratrol, is the grapevine. In cold and wet area of planting pinot noir, especially in the harvest season cold wet area, because the conditions conducive to infect mold, pinot noir of the vines will produce more of the resveratrol to safeguard the health of the self. According to dr west of clay, from the division of the lake's Finn pinot noir wine, has one of the highest resveratrol content, even more than the original production of pinot noir French wave gen similar wine of some times. In the 1980 s, the world health organization survey found that although the French high fat food preference cheese, but tiger rod
Coronary heart disease incidence and mortality rates lower than other western countries, it may be caused by and the French often drink wine containing resveratrol relevant. Since then, concern about resveratrol. So far at least 21 families, 31, has been in 72 kinds of plants are found resveratrol. Resveratrol mainly comes from Polygonaceae Polygonaceae plant tiger Polygonum cuspidatum Sieb rod. Et Zucc. Dry roots and root, grapes, Vitis vinifera fruit plants grape skins and seeds, leguminosae Fabaceae plants the seeds of peanut Arachis hypogaea etc.
Editor this section analysis method
Using C18 column to acetonitrile: water (volume than bonds wherewith 0) solution as mobile phase, using ultraviolet detector in 306 nm place detection. The results showed that the concentration of resveratrol in 10 to 250 μ g/mL, concentration and peak area is good linear relationship between (r = 0.9999); The labeled recovery is 9.25% ~ 10.26%; Minimum detection concentration 0.6 mg/g. Production can adjust the flow velocity and the tiger (and the rod resveratrol enzyme solution transformation.
Edit this paragraph that USES
COX as he 1 selective inhibition