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Product Name:
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Paclitaxel
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Synonyms:
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N-BENZYL-BETA-PHENYLISOSERINE ESTER;PACLITAXEL, TAXUS BREVIFOLIA;PACLITAXEL, TAXUS SPECIES;PACLITAXOL;PACLITAXEL;TAXOL(TM);taxol a;TAXOL EQUIVALENT
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CAS:
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33069-62-4
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MF:
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C47H51NO14
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MW:
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853.91
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EINECS:
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205-285-7
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Product Categories:
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Active Pharmaceutical Ingredients;Pharmaceutical material and intermeidates;Antineoplastics;Antineoplastic;APIs;Antitumors for Research and Experimental Use;Biochemistry;Natural Plant Extract;Intermediates & Fine Chemicals;Pharmaceuticals;Natural Anti-cancer Medical Materials and It's Derivatives;Antitumour;Signalling;Aromatics;Chiral Reagents;Heterocycles;Plant extract
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Mol File:
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33069-62-4.mol
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Paclitaxel Chemical Properties
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mp
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213 °C (dec.)(lit.)
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refractive index
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-49 ° (C=1, MeOH)
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storage temp.
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2-8°C
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solubility
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methanol: 50 mg/mL, clear, colorless
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form
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powder
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color
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white
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Merck
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6982
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Stability:
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Stable. Incompatible with strong oxidizing agents. Combustible.
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CAS DataBase Reference
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33069-62-4(CAS DataBase Reference)
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EPA Substance Registry System
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Benzenepropanoic acid, .beta.-(benzoylamino)-.alpha.- hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S, 12aR,12bS)-6,12b-bis(acetyloxy)- 12-(benzoyloxy)-2a,3,4,4a, 5,6,9,10,11,12,12a,12b-dodecahydro- 4,11-dihydroxy-4a,8,13,13- tetramethyl-5-oxo-7,11-methano- 1H-cyclodeca[3,4]benz[1,2- b]oxet-9-yl ester, (.alpha.R,.beta.S)-(33069-62-4)
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Safety Information
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Hazard Codes
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Xn
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Risk Statements
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37/38-41-42/43-62-68-40-48-20/21/22
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Safety Statements
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22-26-36/37/39-45
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RIDADR
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1544
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WGK Germany
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3
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RTECS
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DA8340700
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F
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10-21
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HazardClass
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6.1(b)
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PackingGroup
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III
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Hazardous Substances Data
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33069-62-4(Hazardous Substances Data)
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Antineoplastic agent isolated from the bark of the Pacific yew tree, Taxus brevifolia. Paclitaxel stabilizes microtubules in the
Molecular formula: C47H5NO14 Molecular weight: 853.92CAS: 33069-62-4Standard: USP28Appearance: white crystalline powderSpecific rotation: -49° ~ 55°Loss on drying: ≤1.0%Heavy metals: ≤20ppmAssay (HPLC): ≥99.5%
[ Separation step ]
A,extraction, to yew as raw material to get contains extracts of
A,extraction, to yew as raw material to get contains extracts of
taxol;
B,remove, and remove the glial tissue extract impurity;
C,separation and purification.
B,remove, and remove the glial tissue extract impurity;
C,separation and purification.
[ Medical function ]
Anti-cancer, effect on kinds of cancer, specially for the ovarian
cancer and breast cancer, Cure rate of 33%, efficient 75%.
[Packing] 500g/barrel, 1kg/Tin or according to customer's requirement
[Storage]: Put in a cool and dry, avoid light, avoid high temperature
[Storage]: Put in a cool and dry, avoid light, avoid high temperature
place.
[Shelf Life]2 years
[Shelf Life]2 years