????Hyaluronic acid (HA) is a straight chain macromolecular mucopolysaccharide composed Of repeat disaccharide units of glucuronic acid and N-acetylglucosamine. It widely consists in the extracellular space of human and animal tissue, vitreum, umbilical cord, skin joints synovia and cockscomb, etc.The commercial HA is commonly a sodium salt, called sodium hyaluronate, habitually called hyaluronic acid. HA is a new biological at home and abroad. Its molecular weight is from several ten thousand to several million. It’s aqueous solution has outstanding moisture keeping ability, high viscoelasticity and lubricity. It is widely used in cosmetics, pharmacy and health and beauty food.
Analysis of Certificate (Food grade)
|
Test Items
|
Specification
|
Result
|
|
Description
|
White powder
|
White powder
|
|
Particle size
|
100% pass through 60 mesh
|
Complied
|
|
PH(0.1%Water Solution)
|
6.0~8.0
|
6.39
|
|
Glucuronic acid
|
≥44.0%
|
46.39%
|
|
Molecular weight
|
800000~1500000
|
0.90X 106
|
|
Sodium hyaluronate
|
≥91.0%
|
95.89%
|
|
Transparency(0.1%Water Solution)
|
≥99.0
|
100.0
|
|
Protein
|
<0.1%
|
0.028%
|
|
Loss on drying
|
≤10.0%
|
7.40%
|
|
Residue on Ignition
|
≤20%
|
15.17%
|
|
Heavy metals
|
<20ppm
|
<10ppm
|
|
Arsenic
|
<2ppm
|
<2ppm
|
|
Bacteria count
|
<100cfu/g
|
<10 cfu/g
|
|
Mold&Yeast
|
<10 cfu/g
|
<10 cfu/g
|
|
Pseudomonas aeruginosa
|
Negative
|
Negative
|
|
Staphylococcus aureus
|
Negative
|
Negative
|
|
Hemolysis
|
Negative
|
Negative
|
|
Viable Hemolytical Streptococci
|
Negative
|
Negative
|
|
|
|
|
|
Name of product
|
Grade
|
Application
|
|
Hyaluronic acid
(Sodium Hyaluronate)
|
Cosmetic grade
|
Cosmetics, all kinds of skin care products,topical ointment
|
|
Food grade
|
Health food
|
|
|
Eye drop grade
|
Eye drops, eye wash, Contact lens care lotion
|
|
|
Intermediate for injection grade
|
Viscoelastic agent in eye surgeries, Injection for the treatment of osteoarthritis, Viscoelastic solution for surgery.
|