Cosmetic Machine V-shape mixer is suitable for mixing the dry powder and granule which belong to flowing materials. The machine consists of two asymmetric barrels where the materials would be moved longitudinally and transversely so that the mixing evenness can be over 99 percent. The mixer can be equipped with vacuum suction system with which the materials can be sucked into the mixing barrels and mixed under hermetic condition. There is no driving mechanism inside the mixer so that it is very clean and meets GMP standard.