Active ingredient: Oat β-Glucans

Botanical source: Avena Fatua L.

Biogenic origin: Wild in central and southern China.

Part of used: Seeds

Specification: 80% β-Glucans

Characters: white or off-white fine powder.

Solubility: Easily soluble in ether,chlorofrom, methanol,ethanol,acetone etc.

Usage: Pharmaceuticals, healthcares.

β-Glucans are known as "biological response modifiers" because of their ability to activate the immune system.[6] Immunologists have discovered that receptors on the surface of innate immune cells called dectin-1 and complement receptor 3 (CR3 or
CD11b/CD18) are responsible for binding to β-glucans, allowing the immune cells to recognize them as "non-self".

Tumoricidal effects

The tumoricidal properties of β-glucans have been studied in several in vitro and in vivo animal models. In a mouse model study, β-1,3 glucan in conjunction with interferon gamma inhibited tumors and liver metastasis. In some studies, β-1,3 glucans enhanced the effects of chemotherapy. In a mouse carcinoma model, β-1,3 glucans did not reduce tumor incidence, but were associated with reduced mortality in combination with cyclophosphamide. In human patients with advanced gastric or colorectal cancer, the administration of β-1,3 glucans derived from shiitake mushrooms, in conjunction with chemotherapy, resulted in prolonged survival times.