Product Main

Specifications

Detailed Product Description
1. Product name: Paclitaxel
2. Active ingredient: Paclitaxel
3. Botanical source: Taxus chinensis
4. Biogenic origin: Wild in central and southern China
5. CAS NO.: 33069-62-4
6. Specification: 98% Paclitaxel
7. Molecular formula: C47H51NO14
8. Molecular Weight: 853.92
9. Characters: White powder.
10. Solubility: Easily soluble in ether ,chlorofrom, methanol, ethanol, acetone etc.
11. Usage: Pharmaceuticals, healthcares and cosmetics.
 
Main Functions
Paclitaxel is one of several cytoskeletal drugs that target tubulin. Paclitaxel-treated cells have defects in mitotic spindle assembly, chromosome segregation, and cell division. Unlike other tubulin-targeting drugs such as colchicine that inhibit microtubule assembly, paclitaxel stabilizes the microtubule polymer and protects it from disassembly. Chromosomes are thus unable to achieve a metaphase spindle configuration. This blocks progression of mitosis, and prolonged activation of the mitotic checkpoint triggers apoptosis or reversion to the G-phase of the cell cycle without cell division.
 
Packing & Storage Condition
Storage:Store in cool & dry place, keep away from strong light and heat.
Shelf Life:24 months when properly stored.
Packing:25/kg paper drum and two plastic-bags inside.