Natural cosmetic preservative polylysine/Non chemical preservative 

 

Company profile

Our company has been in this line for many years with good reputation and considerable funds and a production area of 55,000 square meters. The equipment for production is the most advanced in China. All the systems, including Fermentation System, Purification System and Synchronized Supporting System, are all excellent. Meanwhile, the management system is a successful example. We have obtained ISO9001:2008 quality management system and ISO22000:2006 food safety management system certifications

 

 

 Product profile

Physical properties:

ε-Polylysine is the polymer of L-lysine. It is slightly bitter, hygroscopic, light yellow power. It is soluble in water, slightly soluble in ethanol. The 30-unit homopolymer has a molecular weight of 4700 and an empirical formula of C180H362N60O31. It is still stable when heated (120°C,20min or 100°C,30min). It inhibits the thermophilics. So it is also applied to high temperature process. The activity of ε-Polylysine decreases at the presence of acidic polysaccharide, chloride, phosphate, and Cu2+ while its activity increases with presence of hydrochloric acid, citric acid, malic acid, glycine and glyceride.

 

Safety:

ε-Polylysine is recognized as a very safe substance in the scientific community. ε-Polylysine was generally recognized as safe as food preservative by FDA in October, 2003.It had been approved by FDA for use as an antimicrobial agent in cooked rice or sushi rice at levels up to 50 milligrams per kilogram (mg/kg) of rice. The results of an acute toxicity study and bacterial assays for mutagenicity shows that ε-Polylysine was non-toxic and there was no evidence for mutagenic activity of ε-Polylysine. So ε-Polylysine is absolutely safe to be used as food preservative.

 

Application:

ε-Polylysine has already been used generally as a food additive recognized its safety and advantage in Japan and Republic of Korea. Moreover, ε-Polylysine is acknowledged as a world standard food additive by this recognition of ε-Polylysine as a GRAS material of FDA in US. It can be used in rice, noodles, cakes, snacks, and ice creams, salad, canned foods and meat products.

In addition, ε-polylysine is used in SAP to produce sanitation products, such as sanitation napkin and diapers because of its good absorption of liquid. It can also be used as a carrier for pharmaceutical molecules. Moreover, even in a field other than food, taking advantages of characteristics of polylysine ,the application to fiber, processed goods, cosmetics as an antibacterial agent excellent in kitchen and bath room application has also been developed.

 

MIC (minimum inhibition concentration) Test

Different Types of Microorganisms	Bacteric	MIC  μg/ml	pH
Fungi	Aspergillus niger IFO4416	250	5.6
	Trichophyton mentagrophytes IFO7522	60	5.6
Yeast	Candida acutus IFO1912	6	5.0
	Phaffia rhodozyma IFO10129	12	5.0
	Pichia anomala IFO0146	150	5.0
	Pichia membranaefaciens IFO0577	< 3	5.0
	Rhodotorula lactase IFO1423	25	5.6
	Sporobolomyces roseus IFO1037	< 3	5.0
	Saccharomyces cerevisiae	50	5.0
	Zygosaccharomyces rouxii IFO1130	150	5.6
Gram+ bacteria	Geobacillus stearothermophilus IFO12550	5	7.0
	Bacillus coagulans IFO12583	10	7.0
	Bacillus subtilis IAM1069	< 3	7.3
	Clostridium acetobutylicum IFO13948	32	7.1
	Leuconostoc mesenteroides	50	6.0
	Lactobacillus brevis IFO3960	10	6.0
	L1 plantarum IFO12519	5	6.0
	Micrococcus luteus IFO12708	16	7.0
	Staphylococcus aureus IFO13276	12	7.0
	Streptococcus lactis IFO12546	100	6.0
Gram- bacteria	Raoultella planticola IFO3317	8	7.0
	Campylobacter jejuni	100	7.0
	Escherichia coli IFO13500	50	7.0
	Pseudomonas aeruginosa IFO3923	3	7.0
	Salmonella typhymurium	16	7.0