China Pure Green Coffee Bean Extract 50% Chlorogenic Acid  

 

Description Of Green Coffee Bean Extract

 

Product Name	Green Coffee Bean Extract
Supplier	Hunan World Well-being BioTech Co.,Ltd	Part of used	Seed
Test Method	HPLC	Active ingredient	Chlorogenic acids
Family	Rubiaceae	Function	Weight loss,Anti-oxidation,Anti-agin
Specs  Available	50% 60%	Latin name	Coffea Arabica L.
Appearance	Brown fine powder	CAS NO.	327-97-9
Application	Green Coffee Bean Extract,Green Coffee Bean Extract,Green Coffee Extract Green Coffee Bean Extract Powder are applied in anti-hypertensive effect. Green Coffee Bean Extract Powder are applied in anti-tumor effect. Green Coffee Bean Extract Powder are applied in kidney, and enhance  immune function. Green Coffee Bean Extract Powder are applied in anti-oxidation, anti-aging, anti-aging musculoskeletal. Green Coffee Bean Extract Powder are applied in anti-bacterial, anti-virus. Green Coffee Bean Extract Powder also have other functions: diuretic,  choleretic etc
Our advantage	Green Coffee Bean Extract,Green Coffee Bean Extract,Green Coffee Extract 1. We have our own factory, the quality can be controlled very strictly. 2. Our certification: HALAL,GMP,KOSHER,FDA,ISO22000,ISO14000. 3. Our Purpose: Provide you best quality, best service, best delivery.

What is Green Coffee Bean Extract Chlorogenic Acid?

Chlorogenic acid (CGA) is a natural chemical compound which is the ester of caffeic acid 

and (-)quinic acid. It is an important biosynthetic intermediate. Chlorogenic acid is an 

important intermediate in lignin biosynthesis. This compound, known as an antioxidant, may 

also slow the release of glucose into the bloodstream after a meal.

 

Main Function Of Green Coffee Bean Extract Chlorogenic Acid

1.Green Coffee Bean Extract Chlorogenic acid, long known as an antioxidant with potential 

anti-cancer activity, also slows the release of glucose into bloodstream after a meal.

2.Green Coffee Bean Extract can lower one'sblood sugar level, suppress the appetite, lower 

blood pressure, and reduce levels of visceral fat.

3.Green Coffee Bean Extract Useful in fighting the free radicals in our bodies that can 

damage our cells and contribute to conditions such as cardiovascular disease.

4.Green Coffee Bean Extract Act as an effective painkiller especially for migraine 

medications;

5.Green Coffee Bean Extract Reduce the risk of diabetes;

6.Green Coffee Bean Extract Assist the body to burn at higher proportion of lipids-fats 

compared to carbohydrates

 

Applications Of Green Coffee Bean Extract Chlorogenic Acid

1.Green Coffee Bean Extract are applied in functional food additive & health supplement
2.Green Coffee Bean Extract are applied in Beverage
3.Green Coffee Bean Extract are applied in Cosmetics & personal care products

 

Usage Of Green Coffee Bean Extract Chlorogenic Acid

Green Coffee Bean Extract Chlorogenic acid, long known as an antioxidant with potential anti-

cancer activity,

also slows the release of glucose into bloodstream after a meal.
Green Coffee Bean Extract can lower one'sblood sugar level, suppress the appetite, lower

blood pressure, and reduce levels of visceral fat
Green Coffee Bean Extract useful in fighting the free radicals in our bodies that can damage

our cells and contribute to conditions such as cardiovascular disease.

Green Coffee Bean Extract Act as an effective painkiller especially for migraine medications;
Green Coffee Bean Extract Reduce the risk of diabetes;
Green Coffee Bean Extract Assist the body to burn at higher proportion of lipids-fats

compared to carbohydrates.

 

Health Benefits of Green Coffee Bean Extract Chlorogenic Acid

1. Anti oxidative effects of Green Coffee Bean Extract Chlorogenic Acid

In the investigation of the impact of consumption of a coffee containing high levels of

chlorogenic acids on the oxidation of proteins, DNA and membrane lipids; additionally,

other redox biomarkers were monitored in an intervention trial, found that the oxidation

of DNA, lipids and proteins associated with the incidence of various diseases and the

protection against their oxidative damage may be indicative for beneficial health effects

of coffee.

 

2. Hepatoprotective effects of Green Coffee Bean Extract Chlorogenic Acid

In the investigation of the potential protective effects of chlorogenic acid (CGA) on acute

liver injury caused by lipopolysaccharide (LPS) in mice, found that CGA also decreased the

elevated plasma levels of ALT and AST. At the transcriptional level, CGA pretreatment

suppressed hepatic mRNA expression of toll-like receptor 4 (TLR4), TNF-alpha and NF-

kappaB p65 subunit. In contrast, mRNA level of the transcriptional coactivator PGC-1alpha

was restored by CGA. Finally, CGA reduced the phosphorylation of NF-kappaB p65 subunit

in the liver.

 

3. Anti-obesity of Green Coffee Bean Extract Chlorogenic Acid

in the investigation of the efficacy of chlorogenic acid on altering body fat in high-fat diet

(37% calories from fat) induced-obese mice compared to caffeic acid. Caffeic acid or

chlorogenic acid was supplemented with high-fat diet at 0.02% (wt/wt) dose, found that

Caffeic acid and chlorogenic acid significantly inhibited fatty acid synthase, 3-hydroxy-3-

methylglutaryl CoA reductase and acyl-CoA:cholesterol acyltransferase activities, while

they increased fatty acid beta-oxidation activity and peroxisome proliferator-activated

receptors alpha expression in the liver compared to the high-fat group, and concluded that

caffeic acid and chlorogenic acid improve body weight, lipid metabolism and obesity-related

hormones levels in high-fat fed mice. Chlorogenic acid seemed to be more potent for body

weight reduction and regulation of lipid metabolism than caffeic acid.

 

4. Anti-inflammatory effects of Green Coffee Bean Extract Chlorogenic Acid

In the assessment in vivo of the anti-inflammatory and antinociceptive activities of the

aerial part and root extracts of Scorzonera acuminata, Scorzonera cana var. alpina,

Scorzonera cana var. jacquiniana, Scorzonera cana var. radicosa, Scorzonera cinerea,

Scorzonera eriophora, Scorzonera incisa, Scorzonera laciniata ssp. laciniata, Scorzonera

parviflora and Scorzonera sublanata and theirs effect against inflammation and to relieve

pain, found that Scorzonera cana var. jacquiniana, Scorzonera cinerea, Scorzonera eriophora,

Scorzonera incisa and Scorzonera parviflora possess significant anti-inflammatory and

antinociceptive activity. It has been suggested that flavonoids and chlorogenic acid are

partly responsible for mentioned activities of Scorzonera species.

 

5. Antioxidants of Green Coffee Bean Extract Chlorogenic Acid

In the study of the chemical composition and the antioxidant activity of spent coffee

grounds and coffee husks extracts, obtained by supercritical fluid extraction (SFE) with

CO(2) and with CO(2) and co-solvent, found that the best antioxidant activity was showed

by coffee husk extracts obtained by LPE. The quantification and the identification of the

extracts were accomplished using HPLC analysis. The main compounds identified were

caffeine and chlorogenic acid for the supercritical extracts from coffee husks.

 

6. Antitussive of Green Coffee Bean Extract Chlorogenic Acid

In the investigation of the orally administrated the water extracts in mice. Ammonia

induced mice coughing model was used to evaluate the antitussive activity, found that

only flower bud can be used as the antitussive and expectorant herbal drug. The high

concentration of chlorogenic acid, 3,5-dicaffeoylquinic acid, rutin in flower buds may be

related with the antitussive and expectorant effects of Flos Farfara. To guarantee the

clinical effect, rachis should be picked out before use.

 

7. Rheumatoid Arthritis of Green Coffee Bean Extract Chlorogenic Acid

In the investigation the antiarthritic activities of this compound in adjuvant induced-arthritis

in male Wistar rats, and exploration of the underlying mechanisms of actions in view of

immunological responses, found that CGA efficiently suppressed CD80/86 but failed to

bring any changes in the CD28 count, whereas ibuprofen (standard drug) resulted in highly

significant inhibition of both. We next examined the effect on CD4(+) T cells specific Th1/

Th2 cytokines by flow cytometry and observed that CGA suppressed the Th1 cytokines in a

highly significant manner but elevated Th2 cytokines with dose dependence. Results of the

present investigation suggest that CGA is a potent antiarthritic agent.

 

8. Antioxidant and antimicrobial effects of Green Coffee Bean Extract Chlorogenic Acid

In the investigation of the antioxidant and antimicrobial activities and phenolic components

of different solvent (absolute methanol, absolute ethanol, absolute acetone, 80% methanol,

80% ethanol, 80% acetone and deionized water) extracts of leaves, flowers and bark of

Gold Mohar [Delonix regia (Bojer ex Hook.) Raf.], found that 80% methanol extract produce 

from the leaves exhibited significantly (P < 0.05) higher antioxidant activity, with high

phenolic contents (3.63 g GAE/100 g DW), total flavonoid contents (1.19 g CE/100 g DW),

inhibition of peroxidation (85.54%), DPPH scavenging capacity (IC(50) value 8.89 μg/mL) and

reducing power (1.87). Similarly, this 80% methanol leaves extract also showed superior

antimicrobial activity. HPLC analysis of the 80% methanol extracts for individual phenolics

revealed the presence of gallic, protocatechuic and salicylic acid in leaves; gallic,

protocatechuic, salicylic, trans-cinnamic and chlorogenic acid in flowers, and gallic acid in

bark as the main (amount > 1.50 mg/100 g DW) phenolic acids.

 

9. Apoptosis and mutagenicity of Green Coffee Bean Extract Chlorogenic Acid

In the investigation of whether the PBMCs death induced by cold aqueous extract of

Baccharis articulata (Ba-CAE) a sa result of apoptosis, and whether this extract exerts

mutagenic effects on mice at 24 and 48h after administration.

found that the extract induced PBMCs death by apoptosis and increased the frequency of

micronuclei in bone marrow. The phytochemical study of cold aqueous extract of Baccharis

articulata (Ba-CAE) i showed the presence of flavones as luteolin and acacetin,

caffeoylquinic acids as chlorogenic acid, and tannins,

Packing

Material: In fiber-drums with two-plastic bags inside.

Wight: net weight 25kg/drum; gross weight 28kg/drum

Drum Size & Volume: I.D.42cm × H52cm, 0.08 m3/ Drum

 

Shipping

<50kg by Express, delivery cost according to quantity you order.

50kg <goods<100kg by air, delivery cost is around $10/kg

100kg<goods<500kg by air, delivery cost is around $6-8/kg

goods>500kg by sea, delivery cost is very cheap.

 

Storage

Stored in a cool&dry well-closed container, keep away from moisture and strong light/heat.

 

Shelf life

Two years under well storage situation

 

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1. Mixed container, we can mix different items in one container.
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years
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