| Appearance: | White crystalline powder |
|---|---|
| Application: | Medicine |
| Model Number: | FZ011 |
| Brand Name: | Fengzu |
| Purity: | 99% |
| Type: | Pharmaceutical Intermediates |
| Place of Origin: | China (Mainland) |
| EINECS No.: | 33069-62-4 |
| MF: | C47H51NO14 |
| Other Names: | paclitaxel |
| CAS No.: | 33069-62-4 |
| Name: | Paclitaxel |
| Color: | White crystalline powder |
Quick Details
Specifications
Best quality Paclitaxel,paclitaxel side effects
1. English Name: Paclitaxel
2. Appearance: White crystalline powder
3. CAS No.: 33069-62-4
4. Specification: 99%
5. Molecular Formula: C47H51NO14
6. Molecular Weight: 853.92
7. Solubility: soluble in ethanol, dichloromethane, etc., slightly soluble in acetonitrile, etc.
8. Melting Point: 230~233°C
9. Loss on drying: ≤0.5%
COA
Usage
1. Paclitaxel is a mitotic inhibitor drup used in the treatment of cancer.
2. Isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors.
3. Paclitaxel has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma.
4. Paclitaxel is also used for the prevention of restenosis (recurrent narrowing) of coronary stents; locally delivered to the wall of the coronary artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents.
Paclitaxel is a mitotic inhibitor drup used in the treatment of cancer. It was discovered at Research Triangle Institute (RTI) in 1967 when Monroe E. Wall and Mansukh C. Wani isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors. By 1970, the two scientists had determined the structure of paclitaxel. Paclitaxel has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma. It is sold under the tradename Taxol. Together with docetaxel, it forms the drug category of the taxanes.
Paclitaxel is also used for the prevention of restenosis (recurrent narrowing) of coronary stents; locally delivered to the wall of the coronary artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents. Paclitaxel drug eluting coated stents are sold under the trade name Taxus by Boston Scientific in the United States.
1. English Name: Paclitaxel
2. Appearance: White crystalline powder
3. CAS No.: 33069-62-4
4. Specification: 99%
5. Molecular Formula: C47H51NO14
6. Molecular Weight: 853.92
7. Solubility: soluble in ethanol, dichloromethane, etc., slightly soluble in acetonitrile, etc.
8. Melting Point: 230~233°C
9. Loss on drying: ≤0.5%
COA
|
Item |
Specification |
Method Result |
|
Appearance |
Fine Powder |
Organoleptic Conforms |
|
Color |
White crystalline powder |
Organoleptic Conforms |
|
Odour |
Characteristic |
Organoleptic Conforms |
|
Mesh Size |
80% mesh size |
USP32<786> Conforms |
|
Ash |
≤5.0% |
Eur.Ph.6.0[2.4.16] 3.37% |
|
Pesticides Residue |
Meet USP32<561> |
USP32<561> Conforms |
|
Lead(Pb) |
≤3.0mg/kg |
Eur.Ph6.0<2.2.58>ICP-MS 2.1 |
|
Arsenic(As) |
≤2.0mg/kg |
Eur.Ph6.0<2.2.58>ICP-MS 1.9 |
|
Cadmium(Cd) |
≤1.0mg/kg |
Eur.Ph6.0<2.2.58>ICP-MS 0.7 |
|
Mercury(Hg) |
≤0.1mg/kg |
Eur.Ph6.0<2.2.58>ICP-MS 0.07 |
|
Total Plate Count |
≤1000cfu/g |
USP30<61> 119 |
|
Yeast &Mold |
≤100cfu/g |
USP30<61> 41 |
|
E.Coli. |
Negative |
USP30<62> Conforms |
|
Salmonella |
Negative |
USP30<62> Conforms |
Usage
1. Paclitaxel is a mitotic inhibitor drup used in the treatment of cancer.
2. Isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors.
3. Paclitaxel has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma.
4. Paclitaxel is also used for the prevention of restenosis (recurrent narrowing) of coronary stents; locally delivered to the wall of the coronary artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents.
5. As drugs raw materials of anti-cancer , it is mainly used in pharmaceutical field;
6. As active ingredients of products for preventing breast cancer, ovarian cancer and lung cancer, it is mainly used in health product industry.