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Purity: 99%
Model Number: 484.39
Brand Name: Qualified
Grade Standard: Medicine Grade
Type: Antineoplastic Agents,Cortical hormone
Place of Origin: China (Mainland)
MF: C21H27Na2O8P
Other Names: prednisolone sodium phosphate
CAS No.: 125-02-0

Specifications

Prednisolone phosphate sodium 
 
CBNumber: CB6725349 
English name: Prednisolone phosphate sodium 
Chinese Name: prednisolone sodium phosphate 
MF: C21H27Na2O8P 
MW: 484.39 
CAS: 125-02-0 
 
USP BP CP 
 
Product description:
Prednisolone is a steroid. It prevents the release of substances in the body that cause inflammation.Prednisolone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. Prednisolone may also be used for purposes not listed in this medication guide.
 
Prednisolone is a synthetic adrenal corticosteroid. Corticosteroids are natural substances produced by the adrenal glands located adjacent to the kidneys. Corticosteroids have potent anti-inflammatory properties, and are used in a wide variety of inflammatory conditions such as arthritis, colitis, asthma, bronchitis, certain skin rashes, and allergic or inflammatory conditions of the nose and eyes. There are numerous preparations of corticosteroids including tablets, capsules, liquids, topical creams and gels, inhalers, eye drops, as well as injectable and intravenous solutions. The FDA approved prednisolone in June 1955.
 
Prednisolone is used to achieve prompt suppression of inflammation in many inflammatory and allergic conditions. Examples of inflammatory conditions include rheumatoid arthritis, systemic lupus, acute gouty arthritis, psoriatic arthritis, ulcerative colitis, and Crohn's disease. Severe allergic conditions that fail conventional treatment may also respond to prednisolone. Examples include bronchial asthma, allergic rhinitis, drug-induced dermatitis, and contact and atopic dermatitis. Chronic skin conditions treated with prednisolone include dermatitis herpetiformis, pemphigus, severe psoriasis and severe seborrheic dermatitis. Chronic allergic and inflammatory conditions of the uvea, iris, conjunctiva and optic nerves of the eyes are also treated with prednisolone.
 
Prednisolone also is used in the treatment of blood cell cancers (leukemiias), and lymph gland cancers (lymphomas). Blood diseases involving destruction of platelets by the body's own immune cells (idiopathic thrombocytopenia purpura), and destruction of red blood cells by immune cells (autoimmune hemolytic anemia) can also be treated with prednisolone. Other miscellaneous conditions treated with prednisolone include thyroiditis and sarcoidosis. Prednisolone is also used as a hormone replacement in patients whose adrenal glands are unable to produce sufficient amounts of corticosteroids.
 
How to use prednisolone sodium phosphate
Take this medication by mouth, with food or milk to prevent stomach upset, exactly as directed by your doctor. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
 
There are many brands, strengths, and forms of liquid prednisolone available. Read the dosing instructions carefully for each product because the amount of prednisolone may be different between products. See also Precautions and Storage sections.
 
Follow the dosing schedule carefully. The dosage and length of treatment are based on your medical condition and response to treatment. Your doctor may direct you to take prednisolone 1 to 4 times a day or take a single dose every other day. It may help to mark your calendar with reminders.
 
Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.
 
COA of the Prednisolone
 

Product name

Prednisolone

Appearance

White crystalline powder

Chromatographic purity

Any individual impurity not more than 1.0%

Total impurities not more than 2.0%

0.5%

1.2%

Loss on drying

Not more than 0.5%

0.25%

Residue on ignition

Not more than 0.2%

0.06%

Residual solvents

Methanol≤3000ppm

Methylene Chloride≤600ppm

Chloroform≤60ppm

Tetrahydrofuran≤720ppm

400ppm

Not detect out

Not detect out

Not detect out

Assay

Between 97.0% and 102.0%

99.1%

Micronixation

90% not more than 10 microns

90% not more than 10

aicrons


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