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Usage: Animal Pharmaceuticals
Grade Standard: Feed Grade,Medicine Grade
Type: Antibiotic and Antimicrobial Agents
Place of Origin: China (Mainland)
CAS No.: 1405-10-3

Specifications

High Quality and Neomycin Sulfate Veterinary Medicine Grade CAS: 1405-10-3
Product Description 
Neomycin Sulphate 
CAS No.: 1405-10-3 
Other Names: Neomycin Sulfate 
MF: C23H48N6O17S 
EINECS No.: 215-773-1 
Type: Antibiotic and Antimicrobial Agents 
Characters: White or yellowish-white powder. Odorless or almos. 
Packing: 
20BOU/DRUM 
15BOU/DROM 
25KG/DRUM 
1BOU/TIN, 6TINS/CARTON 

Neomycin sulfate 
CAS: 1405-10-3 
MF: C23H48N6O17S 
MW: 712.72 
EINECS: 215-773-1 
MP >187° C (DEC. ) 
Refractive index 56 ° (C=10, H2O) 
Storage temp. 2-8° C 
Solubility H2O: 50 mg/mL As a stock solution. Stock solutions should be filter sterilized and stored at 2-8° C. Stable at 37° C for 5 days. 
Chemical Properties White powder. 
Usage antibacterial 
Usage Neomycin is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. 


Main Functions: 
Neomycin is overwhelmingly used as a topical preparation, such as Neosporin. It can also be given orally, where it is usually combined with other antibiotics. Neomycin is not absorbed from the gastrointestinal tract and has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia. By killing bacteria in the intestinal tract, it keeps ammonia levels low and prevents hepatic encephalopathy, especially prior to GI surgery. It has also been used to treat small intestinal bacterial overgrowth. It is not given intravenously, as neomycin is extremely nephrotoxic (causes kidney damage), especially compared to other aminoglycosides. The exception is when neomycin is included, in very small quantities, as a preservative in some vaccines - typically 0.025 mg per dose. 

COA:

Items
 

Standards BP2013
 

Standards USP35
 

Results
 


Appearance
 


White or yellowish-white powder, odorless or almost, hygroscopic
 

Complies
 


Identification
 


A, B, C the positive reaction
 


Up to the standard
 


Solubility
 


Very soluble in water, insoluble in acetate, Chloroform, ether
 


9.2%
 


Neomycin C
 


3-15%
 


 
 


Complies
 


Neamine
 


≤2%
 

 
 


Complies
 


Acidity or Alkalinity
 


5.0-7.5
 


5.0-7.5
 


6.9
 


Sulphate
 


27.0-31.0%
 


 
 


28.8%
 


Sulphated ash
 


≤1%
 


 
 


0.4%
 


Loss on drying
 


≤8%
 


≤8%
 


5.5%
 


Specific optical ratation
 


+53.5°- +59.0°
 

 
 


+58.6°
 


Assay
 


≥680I.U. /mg (dry)
 

≥600I.U. /mg (dry)
 

701 I.U. /mg (dry)

662 I.U. /mg (dry)