Specification of matrine

English name: sophora japonica extract powder

Latin name: Sophora flavescens

Active ingredient: matrine

Specification: 98%

Appearance: off white powder

Test method: HPLC

Appearance	White Powder
Odor	Characteristic
Taste	Characteristic
Assay (Matrine)	98%
Testing Method	HPLC
Loss on Drying	≤5.0%
Sieve Analysis	100% Pass 80 mesh
Bulk Density	45-55g/100mL
GMO Free	None
Heavy Metal	<10ppm
Arsenic	<2ppm
Residual Solvents	Eur.Pharm.2000
Total Plate Count	<1000cfu/g
Yeast & Mold	<100cfu/g
E.Coli	Negative
Salmonella	Negative
Irradiation	Co60 Irradiated

Description of matrine

Sophora is a genus of about 45 species of small trees and shrubs in the subfamily Faboideae of the pea

family, Fabaceae. The species are native to southeast Europe, southern Asia, Australasia, the islands of the

Pacific Ocean and western South America. The generic name is derived from sophera, an Arabic name for a

pea-flowered tree.

Matrine and oxymatrine are the two major alkaloid components found in bitter sophora. They are obtained

primarily from Sophora japonica (kushen), but also from Sophora subprostrata (shandougen), and from the

above ground portion of Sophora alopecuroides. An intensive investigation into the pharmacology and clinical

applications of these alkaloids has gone on for the past decade and remains one of the focal points of

Chinese medical research. The main clinical applications of bitter sophora extract are treatment of people with

cancer, viral hepatitis, cardiac diseases, and skin diseases.

Function of matrine

1. Matrine is also be widely used in pesticide;

2. Matrine has function of relieving internal heat;

3. Sophora root extract has effect on anti-bacteria, anti-inflammatory;

4. Matrine is used for suppressing sarcoma S180, anti-tumors;

5. Sophora root extract can cure tonsillitis, mastitis, smooth the asthma etc.when taken orally;

6. Sophora root extract can improve the leucocyte deficiency symptoms so as to enhance the body's immune

function;

7. Sophora root extract is effective in dealing with trichomonad vaginitis, flagellate disease, amoeba dysentery

and fungus dysentery, etc.

Application of matrine

1. Used in Pharmaceutical industry

Treating Gynecological Diseases;

2. Used in Agriculture chemicals

For killing pest.