| Grade Standard: | Medicine Grade |
|---|---|
| Type: | Antipyretic Analgesics and NSAIDs |
| Place of Origin: | China (Mainland) |
| Other Names: | Acetaminophen |
| CAS No.: | 103-90-2 |
Quick Details
Specifications
(Paracetamol) --Antipyretic Analgesics Acetaminophen Paracetamol
Product name:Paracetamol (Acetaminophen)
Quality standard:USP
Assay:98.0-101.0%
CAS NO.: 103-90-2
Molecular formula: C8H9NO2
Molecular mass : 151.16
Physicochemical property:White crystalline powder, odorless,
soluble in hot water, ether, chloroform, etc.
Function:Antipyretic analgesic
This product is acetanilide antipyretic analgesics. By inhibiting ring oxidase and selectivity in the hypothalamus of the temperature regulating center, the synthesis of prostaglandins in peripheral vascular expansion, sweating and antipyretic effect, strength of its antipyretic effect similar to aspirin.
|
Contents |
Specification |
Results |
|
Characters |
White crystalline powder |
Conforms |
|
Identification |
IR,UR,TCL Complies with the test for identification of Paracetamol |
Conforms |
|
Solubility |
Sparingly soluable in water,freely soluable in alcohol,very slightly soluable in methylene chloride. |
Conforms |
|
Melting point |
168-172°C |
169.6-170.0°C |
|
Loss on drying |
≤0.5% |
0.06% |
|
Residue on ignition |
≤0.1% |
0.04% |
|
Chloride |
≤0.014% |
<0.014% |
|
Sulfate |
≤0.02% |
<0.02% |
|
Sulfide |
Conforms |
Conforms |
|
Heavymetals |
≤0.001% |
<0.001% |
|
Readily carbonizable substances |
Conforms |
Conforms |
|
Free p-aminophenol |
≤0.005% |
≤0.005% |
|
Limit of p-chloroacetanilide |
≤0.001% |
<0.001% |
|
Organic volatile impurities |
Conforms |
Conforms |
|
Assay |
98.0%-101.0% |
99.49% |
|
Particle size |
90% no more than 200μm |
Conforms |
|
50% no less than 50μm |
Conforms |
|
|
Conclusion: It complies with the requirements of the USP34 |
||
99% White Powder Antipyretic Analgesics Paracetamol CAS 103-90-2
Use:
1. Antipyretic analgesics, international non proprietary drug called Paracetamol. It is the most commonly used non anti-inflammatory antipyretic analgesic, antipyretic effect similar to aspirin, the analgesic effect is weak, no anti rheumatic effects of anti inflammation, is the best varieties of acetanilide drugs. Particularly suitable for carboxylic acid can not be used drugs patients. For the common cold, toothache embolism. Acetaminophen is intermediate in organic synthesis, hydrogen peroxide stabilizer, photographic chemicals.
2. Used as antipyretic, analgesic, anti rheumatic drugs.
Description:
Chemical Property: Melting point 169-171 Centigrade, the relative density of 1.293 (21/4 Centigrade). Soluble in ethanol, acetone and water, insoluble in water, not soluble in petroleum ether and benzene. No smell, taste bitter. Saturated aqueous solution pH value 5.5-6.5.
Synonyms: 4-Acetamidophenol; 4-ACETAMINOPHENOL; 4'-HYDROXYACETANILIDE; 4-HYDROXYACETANILIDE; 4-(ACETYLAMINO)PHENOL; Acetaminophen; ACETYL-P-AMINOPHENOL; AKOS BBS-00008094

