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Grade Standard: Medicine Grade
Type: Antipyretic Analgesics and NSAIDs
Place of Origin: China (Mainland)
Other Names: Acetaminophen
CAS No.: 103-90-2

Specifications

(Paracetamol) --Antipyretic Analgesics Acetaminophen Paracetamol
Product name:Paracetamol (Acetaminophen)

Quality standard:USP

Assay:98.0-101.0%

CAS NO.: 103-90-2

Molecular formula: C8H9NO2

Molecular mass : 151.16

Physicochemical property:White crystalline powder, odorless,

soluble in hot water, ether, chloroform, etc.

Function:Antipyretic analgesic
This product is acetanilide antipyretic analgesics. By inhibiting ring oxidase and selectivity in the hypothalamus of the temperature regulating center, the synthesis of prostaglandins in peripheral vascular expansion, sweating and antipyretic effect, strength of its antipyretic effect similar to aspirin.

Contents

Specification

Results

Characters

White crystalline powder

Conforms

Identification

IR,UR,TCL Complies with the test for identification of Paracetamol

Conforms

Solubility

Sparingly soluable in water,freely soluable in alcohol,very slightly soluable in methylene chloride.

Conforms

Melting point

168-172°C

169.6-170.0°C

Loss on drying

≤0.5%

0.06%

Residue on ignition

≤0.1%

0.04%

Chloride

≤0.014%

<0.014%

Sulfate

≤0.02%

<0.02%

Sulfide

Conforms

Conforms

Heavymetals

≤0.001%

<0.001%

Readily carbonizable substances

Conforms

Conforms

Free p-aminophenol

≤0.005%

≤0.005%

Limit of p-chloroacetanilide

≤0.001%

<0.001%

Organic volatile impurities

Conforms

Conforms

Assay

98.0%-101.0%

99.49%

Particle size

90% no more than 200μm

Conforms

50% no less than 50μm

Conforms

Conclusion: It complies with the requirements of the USP34

99% White Powder Antipyretic Analgesics Paracetamol CAS 103-90-2

Use:
1. Antipyretic analgesics, international non proprietary drug called Paracetamol. It is the most commonly used non anti-inflammatory antipyretic analgesic, antipyretic effect similar to aspirin, the analgesic effect is weak, no anti rheumatic effects of anti inflammation, is the best varieties of acetanilide drugs. Particularly suitable for carboxylic acid can not be used drugs patients. For the common cold, toothache embolism. Acetaminophen is intermediate in organic synthesis, hydrogen peroxide stabilizer, photographic chemicals.
2. Used as antipyretic, analgesic, anti rheumatic drugs.

Description:
Chemical Property: Melting point 169-171 Centigrade, the relative density of 1.293 (21/4 Centigrade). Soluble in ethanol, acetone and water, insoluble in water, not soluble in petroleum ether and benzene. No smell, taste bitter. Saturated aqueous solution pH value 5.5-6.5.

Synonyms: 4-Acetamidophenol; 4-ACETAMINOPHENOL; 4'-HYDROXYACETANILIDE; 4-HYDROXYACETANILIDE; 4-(ACETYLAMINO)PHENOL; Acetaminophen; ACETYL-P-AMINOPHENOL; AKOS BBS-00008094