[ pharmacological action]
This article first shift in the body for 5 - fluoro - 2 - DNA nucleotides uracil, which inhibit thymine nucleotide synthetase, blocking DNA nucleotide into DNA thymine, uracil and inhibit the biosynthesis of addition, by preventing uracil and whey acid mixed with RNA, the role of suppressing RNA synthesis. This product is a cell cycle specificity of drugs, mainly inhibit the S phase cells.

[ indications ]
This product has a wide spectrum of antineoplastic, mainly used in the treatment of digestive tract tumor, or larger dose fluorouracil chorionic carcinoma treatment. Is often used to treat breast cancer, ovarian cancer, lung cancer, cervical cancer, bladder cancer and skin cancer, etc.

[ usage and dosage ]
Fluorouracil for intravenous injection or intravenous drip used dose differs very big. Single medicine intravenous dose is commonly by 10 to 20 mg/kg body weight 1, amuse (5 ~ 10, 5 ~ 7 grams per treatment (10 grams). If the intravenous drip, usually by the surface area of 1, 300-500 mg/m2, amuse (3 ~ 5 days, every time an intravenous drip time shall not be less than 6 ~ 8 hours; When intravenous drip infusion pump continuous dosing maintain available 24 hours. Used for primary or metastatic liver cancer, we adopt artery intubation with drug. Intraperitoneal injection according to the surface area of a 500-600 mg/m2.2 ~ 4 times, 1 times a week for 1 course of treatment.