| Brand Name: | Flarebio |
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| Place of Origin: | China (Mainland) |
Quick Details
Specifications
| Product Name: | Mouse anti- human Timp1 monoclonal antibody |
| Product Type : | Monoclonal Antibody |
| Code : | CSB-MA0235601A0m |
| Size : | 100ug |
| Uniprot NO. : | |
| Storage : | Shipped at 4°C Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze. |
| Immunogen : | human Timp 1 |
| Raised in : | mouse |
| Species Reactivity : | human |
| Specificity : | specific for Human Timp1 denatured and native forms |
| Tested Applications : | ELISA, WB, and other possible application |
| Relevance : | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. |
| Form : | liquid |
| Conjugate : | Non-conjugated |
| Storage Buffer : | Preservative: 15mmol/L NaN3Constituents: 0.1mol/L Nacl |
| Purification method : | Protein G purified |
| Isotype : | IgG2a |
| Clonality : | monoclonal |
| Alias : | timp-1 |
| Protocol : |
Protocol may be improved. Please feel free to contact FLAREBIO product specialist to obtain the latest version.
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| Target details : | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. |
| HGNC : | |
| RGD : | |
| MGI : | |
| BIOWWW : | |
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