Y chromosome mircodeletions test kit

Compitable instrument: Open real time PCR instruments

Sensitivity: 1000copies/ml

Packing:20tests/kit

Result: 1.5 hours

According to European Academy of Andrology(EAA) and European Molecular Genetics Quality Network(EMQN) best practice guidelines for molecular diagnosis of Y-chromosomal microdeletions, the kit was designed in two tubes multiplex PCR florescence amplification in four channel(FAM/VIC/ROX/Cy5),detection the six Sequence Taq Site(STS) microdeletions in AZFa,AZFb,AZFc area, simultaneously setup two gene as internal control, separately as Sex-determining region of the Y chromosome(SRY) and Zinc finger protein ZFX/ZFY, who monitor the whole reaction procedure from sample collection, Nucleic Acid extraction and PCR amplification.

 Y Chromosomal microdeletion is one of main reasons caused male infertility.

According to WHO statistics that 15% couples were suffering from infertility.

The third disease threaten to human health.
Over 30% of them are caused by genetic abnormalities.

After the Klinefelter syndrome, Y-chromosomal microdeletions are the second most frequent genetic cause of male infertility