Product Name:
USP5 Antibody
Code : CSB-PA025742LA01HU
Immunogen : Recombinant human Ubiquitin carboxyl-terminal hydrolase 5 protein
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA;Not yet tested in other applications.
Relevance : Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored \'Lys-48\'-linked polyubiquitin disassembly. Binds linear and \'Lys-63\'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
Form : Liquid
Conjugate : Non-conjugated
Storage Buffer : Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification method : >95%,Protein G purified
Isotype : IgG
Clonality : Polyclonal
Alias : Ubiquitin carboxyl-terminal hydrolase 5,Deubiquitinating enzyme 5,Isopeptidase T,Ubiquitin thioesterase 5,Ubiquitin-specific-processing protease 5,USP5,ISOT
Species : Human