1. During the HIPEC procedure the surgeon will continuously circulate a heated sterile solution containing a chemotherapeutic agent throughout the peritoneal cavity, for a maximum of two hours. The HIPEC procedure is designed to attempt to kill any remaining cancer cells. The sterile solution will then be drained away and the surgical incision will be closed.

2. The procedure also improves drug absorption and effect with minimal exposure side effects of chemotherapy can be avoided.

One that involves surgically removing cancerous tumors from the abdominal cavity, then bathing the cavity with hot chemotherapy to kill any cancer cells left in there.

Q: What is the principle of HIPEC?

The idea behind the treatment is that heat at 42 degrees Celsius (107.6 degrees Fahrenheit) is also be kill cancer cells without affecting normal cells in the body. In addition, heat supposedly makes the chemotherapy more powerful at killing cancer cells. As well as softens the nodules of the tumors so that the chemotherapy can more easily penetrate them.

CRS with HIPEC is safe and feasible at tertiary institutions with fledgling programs. PCI is an accurate predictor of surgical outcomes.

Hot Chemo bath therapy

HIPEC is designed to kill any remaining cancer cells once all visible disease is removed surgically.

HIPEC is performed at the end of surgery to remove abdominal tumors. Once all visible tumors have been removed (called " cyto-reduction" ) the surgeon continuously circulates a heated, sterile chemotherapy solution throughout the peritoneal cavity for up to 90 minutes The HIPEC procedure is designed to attempt to kill any remaining cancer cells. That cannot be seen. The solution is then removed and the incision closed.

Giving the chemotherapy in the abdomen at the time of surgery allows for greater concentrations of the drug where it is needed.

Adding heat has a threefold advantage:

Heat above 41 degrees Celsius more effectively kill cancer cells while having fewer effects on normal cells.

 Heat allows the chemotherapy to penetrate a few millimeters and kill cancer cells that cannot be seen .

The chemotherapy does can be higher than that given intravenously because it is not absorbed by the body in the same way. In this way, the normal side effects of chemotherapy can be avoided.

There is substantial clinical evidence that HIPEC is an effective treatment for patients with pseudomyxoma peritonei, mucinous adenocarcinoma of the appendix, and peritoneal mesothelioma.

Additionally, peritoneal metastases from colon cancer ca be successfully treated in a significant number of patients.

Our team is one of the most experienced in the world at this procedure. Our three surgeonsare experts in complex abdominal surgery for peritoneal metastates. They have performed hundreds of cytoreductive/ HIPEC surgeries, and typically perform2-3 procedures a week.

Hot chemo bath therapy HIPEC or heated intraperitoneal chemoperfusion, is a procedure to treat advanced abdominal cancers.

HIPEC is designed to kill any remaining cancer cells once all visible disease is removed surgically.

HIPEC is performed during a surgery to remove an abdominal tumor. Once the tumor has been removed.( " cytoreduction" ) the surgeon continuously circulates a heated, sterile chemotherapy solution throughout the peritoneal cavity for up to 90 minutes.

Candidate

HIPEC therapy may be appropriate for

Cytoreductive surgery followed by HIPEC is a comprehensive surgical treatment for certain patients with malignancies arising from or confined to the peritoneal cavity including : cancers that have spread to the lining of the peritoneal cavity. Some types of cancers are very difficult to treat. Cancer that has spread to the lining surfaces of the peritoneal ( abdominal) cavity from primary colorectal cancer, appendiceal cancer, or mesothelioma and pseudomyxoma peritonei –known as peritoneal carcinomatosic –are such cancers.

Q: What is HIPEC?

Hyperthermic Intraperitoneal chemotherapy(HIPEC) is a highly concentrated. Heated chemotherapy treatment that is delivered directly to the abdomen during surgery.Cytoreductive surgery is the aggressive removal of tumors in the abdomen. The surgery is followed by heated chemotherapy. Hyperthermic Intraperitoneal chemotherapy( HIPEC) to prevent new cancerous cells from developing. The heated chemotherapy bathes the abdominal nin-visible or microscopic tumor cells. Heat helps kill the cancer cells and also enhances the effect of chemotherapy.

To treat the entire abdominal cavity, the heated chemotherapy solution is pumped in a constant flow through tubes in the abdomen. This allows the heated chemotherapy to reach the cancer cells that could potentially form

HIIC  ( heated intraoperative intraperitoneal chemotherapy)

          Intraperitoneal chemo hyperthermia

          Continuous hyperthermic Peritoneal perfusion

          (HIPEC) Hyperthermia Intraperitoneal Chemotherapy

          Hyperthermic perfusion

          Chemohyperthermic peritoneal perfusion (CHPP)