Product Name: Axitinib CAS: 319460-85-0
Synonyms: AXITINIB; Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-; N-METHYL-2-{[3-((E)-2-PYRIDIN-2-YLVINYL)-1H-INDAZOL-6-YL]SULFANYL}BENZAMIDE; N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide; AVERMECTINB; Axitinib for research; AG 013736; N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
CAS: 319460-85-0
MF: C22H18N4OS
MW: 386.47
Product Categories: All Inhibitors; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Protein Kinase Inhibitors and Activators; Pfizer compounds; API; AG 013736
mp 213-215°C
storage temp. -20°C Freezer
Chemical Properties Off-White Solid
Usage A tyrosine kinase inhibitor; used in cancer therapy.
Usage Axitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively.
Usage Axitinib is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively.
Usage Axitinib is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.