Pharmaceutical Raw Materials CAS 16595-80-5 Levamisole Hydrochloride for Immunomodulator

Quick Detail:

Product name	Levamisole hydrochloride
CAS register number	16595-80-5
EINECS	240-654-6
Molecular formula	C11H13ClN2S
MW	240.75
Assay	99%
Appearance	White to almost white crystalline powder
Usage	Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.
Minimum order quantity	10g
Shipping	By express courier
Shipping leading time	Within 24 hours after receiving the payment
Payment options	Western Union , MoneyGram , T/T , Bitcoin
Price	Negotiated

Description:

1.Properties Levamisole refers to Levo tetramisole, it is the Levo Isomer of tetramisole. It can selectively inhibit succinate dehydrogenase in parasite's muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite's muscle metabolism lacks of oxygen and leads to decreasing of energy.

2.L-isomer is active against helminthes with 1-2 times higher active efficiency and lower toxic and side effects than tetramisole. It is a broad spectrum anthelmintic with a very good activity against roundworms, hookworms, whipworms, and strongyloises stercoralis. It is an immunomodulator and has effect on rheumatic disorders.Levamisole is also a good alternative in cases of benzimidazole resistance.

Applications:

It can selectively inhibit succinate dehydrogenase in parasite's muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite's muscle metabolism lacks of oxygen and leads to decreasing of energy. Levamisole is also a good alternative in cases of benzimidazole resistance.

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Abstract

Levamisole hydrochloride was an efficient microfilaricide when used in dogs at a dosage of 10 mg/kg twice daily for 14 days. Increasing the dose rate every 3 days to 10 mg/kg twice daily and maintaining it at 10 mg/kg twice daily for a further 8 days, was also effective but a dosage of 5 mg/kg twice daily for 21 days was less effective and a dose rate of 20 mg/kg was efficient, but toxic.

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