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Purity: 99%
Model Number: CAS NO.: 595-33-5
Brand Name: NJ
Grade Standard:
Type:
Place of Origin: China (Mainland)
EINECS No.: 209-864-5
MF: C24H32O4
CAS No.: 595-33-5

Specifications

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Now I will introduce our Megestrol Acetate:
Megestrol Acetate steroid raw powder best supplier

Megestrol Acetate CAS NO. : 595-33-5
Megestrol Acetate EINECS: 209-864-5
Megestrol Acetate Assay: 99%
Megestrol Acetate Molecular Formula: C24H32O4
Megestrol Acetate Molecular Weight: 384.51
Appearance: White or light yellow crystalline powder (methanol), odorless and tasteless. Melting point 214-216. Soluble in acetone, slightly soluble in ethanol, ethyl ether, insoluble in water

Product Description
Megestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects.

Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same as megestrol, which is a closely related but different compound.
Megestrol acetate has powerful antiandrogenic and antiestrogenic effects in humans at sufficient doses, capable of decreasing circulating androgen and estrogen concentrations to castrate levels in both sexes and significantly lowering the expression of the androgen receptor (AR) and the estrogen receptor (ER) in the body; as an example, one study in men with benign prostatic hyperplasia who were treated with 120-160 mg of megestrol acetate per day for 3 to 11 days found average decreases in AR quantity of 73% and 86% in the cytoplasm and nucleus of prostatic cells, respectively. [12] These actions are likely the result of a strong activation of the PR, which suppresses the secretion of the gonadotropins-peptide hormones responsible for signaling the body to produce not only progesterone but also the androgens and the estrogens-from the pituitary gland as a form of negative feedback inhibition, and hence downregulates the hypothalamic-pituitary-gonadal (HPG) axis, resulting in decreased levels of the sex hormones and their associated enzymes, carriers (e. g., sex hormone-binding globulin), and receptors. It is the antiandrogenic and antiestrogenic effects of megestrol acetate mediated by suppression of the HPG axis that are believed to be largely responsible for its beneficial effects against androgen and estrogen-sensitive cancers, respectively.


Packaging & Delivery
We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.



Our advantages

1) Our company is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
2) Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
3) Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand.
4) Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.
5) High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS, EMS, etc



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