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Quick Details

Appearance: White Crystalline Powder
Application: pharmaceutical material
Model Number: 859-18-7
Brand Name: NJBN STEROID
Purity: 99%
Type: Pharmaceutical Intermediates
Place of Origin: China (Mainland)
MF: C18H35ClN2O6S
CAS No.: 859-18-7

Specifications

Super Pure 99% Lincomycin Hydrochloride CAS 859-18-7 for Infection Treatment

1. Quick Detail:

Product name

Lincomycin hydrochloride

Synonyms

METHYL 6,8-DIDEOXY-6-(1-METHYL-4-PROPYL-2-PYRROLIDINECARBOXAMIDO)-1-THIO-D-ERYTHRO-ALPHA-D-GALACTOOCTOPYRANOSIDE HYDROCHLORIDE; LINCOMYCIN HCL; LINCOMYCIN HYDROCHLORIDE; LINCOCIN HYDROCHLORIDE; ALPHA-METHYL-6,8-DIDEOXY-6-[1-METHYL-4-PROPYL-2-PYRROLIDINECARBOXAMIDO]-1-THIO-D-ERYTHRO-D-GALACTOOCTOPYRANOSIDE HYDROCHLORIDE; U-10149A; N-[2-HYDROXY-1-(3,4,5-TRIHYDROXY-6-METHYLSULFANYL-OXAN-2-YL)-PROPYL]-1-METHYL-4-PROPYL-PYRROLIDINE-2-CARBOXAMIDE; lincomycin standard solution

Original

China

CAS

859-18-7

EINECS

212-726-7

Molecular formula

C18H35ClN2O6S

MW

443

MP

156-158C

Drug class

oral

Brand name

NJBNSteroid

Leading time

within 24 hours upon receipt of payment

Delivery

Fast and secure shipping byEMS, DHL, TNT, FedEx, UPS

Purity

99%

Package

Discreetand Hidden package according to specific requirement

Appearance

Certification

SGS, ISO 9001, KOSHER

Payment Terms

Western Union, Money Gram , T/T, Bitcoin

Minimum Order Quantity

5g

Price

Negotiable

Usage

Lincomycin hydrochloride is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans


1. Key Specification Index:

Item

Standard

Result

Characteristics

white or almost white crystalline powder

Conform

Identification

Should meet related requirements

Conform

Appearance of solution

Should meet related requirements

Passed

PH

3.5-5.5

4.5

Specific optical rotation

+135°~+150°

+143°

Lincomycin B

5.0% max

2.9%

Heavy metals

5ppm max

Conform

Residue on ignition

0.5% max

0.1%

Water

3.1-4.6%

4.3%

Bacterial endotoxins

smaller than 0.5IU/mg

smaller than0.5IU/mg

Assay

Not less than 89.5% and not more than 102.0% of lincomycin (C18H35ClN2O6S))

98. 4%%


1. Description:

Lincomycin hydrochloride appears as a white crystalline powder at room temperature with slight odor or special smell and bitter taste. It is soluble in water and methanol. Feed often applied its hydrochloride salt form. The drug is the product during the growth of the population of the Streptomyces genus (Streptomyces lincolnensis), as a kind of lincosamides alkaline antibiotics.

Through interaction with the 50S ribosomal subunit of the sensitive bacteria, it prevents the peptide chain elongation, thereby inhibiting protein synthesis of the bacterial cell with antimicrobial effect.

Lincomycin hydrochloride mainly has strong antibacterial effect against Gram-positive bacteria, and some anaerobic bacteria as well as Mycoplasma with its antibacterial spectrum narrower than erythromycin.

Items Tested

Specification

Result

Characters

White or almost white crystalline powder

Confirms

Assay (HPLC)

99.0--101.0%

99.8%

Loss on Drying

Not more than 0.5%

0.16%

Residue on ignition

Not more than 0.2%

0.06%

2. Application:

Lincomycin hydrochloride has therapeutic effect when being used for the treatment of Sepsis, female genital tract, endometritis, non-gonococcal tubo-ovarian abscess, pelvic cellulitis; postoperative vaginal annex infections, peritonitis, abscesses, pneumonia, lung abscess, skin and soft tissue infections caused by most Gram-negative bacteria and some anaerobic bacteria. It can also be used for the surgical adjuvant treatment of Sepsis caused by streptococci and staphylococci, bone and joint infections, chronic bone and joint infections as well as the acute hematogenous osteomyelitis of Staphylococcus aureus.

1. Oral formulations is suitable for treating respiratory infections, abdominal infection, female reproductive tract infections, pelvic infections, skin and soft tissue infections caused by sensitive Staphylococcus aureus and Streptococcus pneumoniae.
2. In addition to the treatment of the above infections, injected formulations are suitable for treatment of severe infections caused by streptococcus, pneumococcus and staphylococcus such as the surgical adjuvant therapy of septicemia, bone and joint infections, chronic bone and joint infections and Staphylococcus-induced acute hematogenous osteomyelitis.
3. Lincomycin hydrochloride may also be used for the treatment of infectious diseases in patients allergic to penicillin or not suitable for administration of penicillin-type drugs.
Tablets: Each tablet 0.25g, 0.5g; Injection: each 0.2g, 0.6g.

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Lead Time

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Tracking number

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