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Quick Details

Appearance: White crystal powder
Application: Used as an antiasthmatic
Model Number: 2392-39-4
Brand Name: NJBN STEROID
Purity: 99%
Type: Pharmaceutical Intermediates
Place of Origin: China (Mainland)
MF: C22H28FNa2O8P
CAS No.: 2392-39-4

Specifications

Dexamethasone 21-phosphate disodium salt CAS 2392-39-4for anti-inflammatory

English Synonyms: decadronphosphate; dexadreson; dexagro; dexamethasonedisodiumphosphate; disodiumdexamethasonephosphate; disodiumsalt, (11beta, 16alpha)-y); megacort; pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonoox

CAS NO. : 2392-39-4

EINECS: 219-243-0

Assay: 99%

Molecular Formula: C22H28FNa2O8P

Molecular Weight: 516.4

Quality Standard: CP2002/CP2005/USP/BP/EP

Packing: 1kg/tin, 5kg/tin

Appearance: White to white crystalline powder

Usage: This product adrenal cortex hormone class medicine. Have anti-inflammatory, anti-allergic and immunosuppressive pharmacological effects and other

2. Description:

Dexamethasone 21-phosphate disodium salt is a system glucocorticoid with anti-inflammatory properties. Dexamethasone 21-phosphate disodium salt is the pro-drug, which is converted to dexamethasone. It stimulates uptake of glutamine in the cerebral cortex and induces apoptosis. Additionally, it is an inhibitor of the sodium phosphate symporter and GR activator.

3. Medical Uses

This is an anti-inflammatory glucocorticoid and corticosteroid. It is used in the treatment of hypertensionI, in eye and ear preparations and in systemic preparations. It is administered by injection, by inhalation, or applied to the skin and conjunctiva. Further research may identify additional product or industrial usages of this chemical.


4. Technical Test Sheet

Product name

Dexamethasone 21-phosphate disodium salt

Appearance

White crystalline powder

Chromatographic purity

Any individual impurity not more than 1.0%

Total impurities not more than 2.0%

0.35%

0.8%

Loss on drying

Not more than 0.5%

0.12%

Residue on ignition

Not more than 0.2%

0.05%

Residual solvents

Methanol≤3000ppm

Methylene Chloride≤600ppm

Chloroform≤60ppm

Tetrahydrofuran≤720ppm

356ppm

Not detect out

Not detect out

Not detect out

Assay

Between 97.0% and 102.0%

98.5%

Micronixation

90% not more than 10 microns

90% not more than 10

aicrons



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