Hydrocortisone  CAS 50-23-7 as Adrenal Cortex Hormones Drug

1. Hydrocortisone

English Synonyms: 11,17a,21-Trihydroxy-4-pragnene-3,20-dione;11-beta,17,21-trihydroxypregn-4-ene-3,20-dione;11beta,17,21-Trihydroxypregn-4-ene-3,20-dione;11-beta,17-alpha,21-trihydroxy-4-pregnene-3,20-dione;11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione;11-beta,17-alpha-trihydroxypregnane-4-ene-3,20-dione;11-beta-hydrocortisone;11beta-Hydrocortisone

CAS NO.: 50-23-7

Assay: 98%

Molecular Formula:C21H30O5

Molecular Weight:362.46

Melting point: 214-220℃

Specifications: USP32/EP6

Packing:1kg/tin

Appearance: White or white crystalline powder, odorless, bitter taste. Degenerate case of light

Usage: Biochemical studies, adrenal cortex hormones drugs;

2.  Description:

Hydrocortisone (INN, USAN, BAN) is a name for cortisol when it is used as a medication. Hydrocortisone is used to treat people who lack adequate naturally generated cortisol. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. 

Cortisol is a steroid hormone, in the glucocorticoid class of hormones, and is produced in humans by the zona fasciculata of the adrenal cortex within the adrenal gland. It is released in response to stress and low blood-glucose concentration.

3.Medical Uses:

Uses of This Medicine

Hydrocortisone is a steroid medication that treats inflammation in the body.

The drug comes in an oral form to take by mouth, and a topical form to apply to the skin. It's available over-the-counter (OTC) and with a prescription for higher-strength formulations.

Hydrocortisone provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, asthma, blood or bone marrow problems, eye or vision problems, lupus, skin conditions, ulcerative colitis, and flare-ups of multiple sclerosis. Hydrocortisone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.

Technical Test Sheet

Test Items	Specification	Test Results
Description	White or almost white crystalline powder	White crystalline powder
Melting Point	191.0~193.0oC	192oC
Loss of drying	≤1.0%	0.5%
Heavy Metal	≤20ppm	15ppm
TLC	Only one spot	Only one spot
Assay	≥99.5%	99.91%
Conclusion	It complies with the USP 32.

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