| Appearance: | White to off-white powder |
|---|---|
| Application: | pharmaceutival material |
| Model Number: | 148553-50-8 |
| Purity: | 99% |
| Type: | Pharmaceutical Intermediates |
| Place of Origin: | China (Mainland) |
| MF: | C8H17NO2 |
| CAS No.: | 148553-50-8 |
Quick Details
Specifications
Pregabalin
CAS: 148553-50-8
MF: C8H17NO2
MW: 159.23
mp 194-196°C
storage temp. Store at RT
Chemical Properties Off-White Solid
Usage S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.
Purity: 99%
Usage: API
Package: 1KG foil bag; 25Kg drum
| Product name: | Pregabalin |
| Other Name | 3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID; (3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID; PREGABALIN; Pregablin; 3-(Aminomethyl)-5-methyl-hexanoicacid; PREDNISOLONESODIUMPHOSPHATE; (R)-Pregabalin; (S)-Pregabalin |
| Original | China |
| CAS | 148553-50-8 |
| Molecular formula | C8H17NO2 |
| Brand name | NJBNSteroid |
| Leading time | within 24 hours upon receipt of payment |
| Delivery | Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS |
| Purity | 99% |
| Package | Discreet and Hidden package according to specific requirement |
| Appearance | White Powder |
| Certification | SGS, ISO 9001 |
| Payment Terms | Western Union, Money Gram , T/T, Bitcoin |
| Minimum Order Quantity | 10g |
| Price | Negotiable |
| Usage | Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin. Pregabalin is marketed by Pfizer under the trade nam |
2. Description of Pregabalin
Pregabalin is a new antiepileptic drug, having a γ-amino butyric acid structure on its molecular structure, which has anticonvulsant effects, and is successfully developed by the company Pfizer for the treatment of peripheral neuropathic pain, or adjuvant treatment of partial seizures.
In December 2008, the US Food and Drug Administration (FDA) approved pregabalin (trade name "Lyrica") for the treatment of diabetic peripheral neuropathic pain (DPN) and postherpetic neuralgia (PHN)which are Both the most common neuropathic pains.
Neuropathic pain is one of the most difficult chronic pain syndromes to treat , dull pain, burning, tingling as the main feature, there are a lot of incentives of neuralgia, diabetes, infections (such as herpes zoster), cancer and AIDS, etc. Can cause neurological pain, in Europe about 3% of the population suffer from neuralgia torture.
3. Clinical Application of Pregabalin
Pregabalin is used to relieve neuropathic pain (pain from damaged nerves) that can occur in your arms, hands, fingers, legs, feet, or toes if you have diabetes or in the area of your rash if you have had shingles (a painful rash that occurs after infection with herpes zoster).
It is also used to treat fibromyalgia (a long-lasting condition that may cause pain, muscle stiffness and tenderness, tiredness, and difficulty falling asleep or staying asleep).
Pregabalin is used with other medications to treat certain types of seizures in people with epilepsy. Pregabalin is in a class of medications called anticonvulsants. It works by decreasing the number of pain signals that are sent out by damaged nerves in the body. 4. Technical Analysis
| ITEMS | STANDARDS | RESULTS |
| Appearance | A white to off white powder | White powder |
| Identification | A. Meets the requirement | Complies |
| B. IR: similar to Reference Substance | Complies | |
| Loss on drying | ≤0.5% | 0.21% |
| Specific Rotation | +10.0°~+13.0° | +10.8° |
| Related Substances |
Any single impurity ≤0.1% Total impurity ≤0.8% |
0.05% 0.10% |
| Purity By HPLC R-isomer | ≤0.15% | 0.10 |
| Residue on ignition | ≤0.1% | 0.05% |
| Residual solvents |
Isopropyl alcohol ≤5000ppm Ethyl Acetate ≤5000ppm |
150ppm 250ppm |
| Heavy metals | ≤10ppm | Complies |
| Chlorides | ≤0.05% | Complies |
| Assay | 98%~102.0% | 99.8% |
| Conclusion | Analyse according to Factory Standard , Conform | |
LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a clear, colorless solution contained in a 16 fluid ounce white HDPE bottle with a polyethylene-lined closure. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben, propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.
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| Packing | According to different countries and quantity of orders |
| Lead Time | Arranged within 24 hours upon receipt of your payment |
| Photos | Photos of parcel would be offered to tell apart the steroids in advance |
| Delivery Time | Usually 4-6 working days to reach destinations |
| Tracking number | Offered once it is released on the Net . Normally within 24hours upon the receipt of payment. |
| After-sale service | 24/7 online for problems and concern related |
1. High quality and standard:
Standard: Enterprise Standard;
All Purity≥98%;
We are manufacturer and can provide high quality products with factory price.
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Parcel can be sent out within 24 hours after payment. Tracking number is available;
Secure and discreet shipment (EMS , DHL , TNT , FedEx , UPS). Various transportation methods for your choice;
Customs pass rate ≥99%;
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