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Quick Details

Appearance: White crystalline powder
Application: Sodium channel blocker, local anesthetic.
Model Number: 14252-80-3
Brand Name: NJBN STEROID
Purity: 99%
Type: Pharmaceutical Intermediates
Place of Origin: China (Mainland)
MF: C18H28N2O.ClH
CAS No.: 14252-80-3

Specifications

Bupivocoine HCl

Synonyms: Bupivacaine hydrochloride; 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide

CAS: 14252-80-3

Assay: 98.0%-101.0%

Standard: USP32

Packing: 1kg/foil bag

MF: C18H28N2O. ClH

MW: 324.89

Character: White Solid. Mp 249-251℃.

Usage: Sodium channel blocker, local anesthetic.



Product name: Ropivacaine hydrochloride
Other Name BUPIVACAINE HYDROCHLORIDE; (+, -)-1-butyl-2', 6'-pipecoloxylididemonohydrochloride, monohydrate; 1-butyl-2', 6'-pipecoloxylididehydrochloride(+-); 2-piperidinecarboxamide, 1-butyl-n-(2,6-dimethylphenyl)-monohydrochloride, m;ah-2250; marcainehydrochloride; dl-1-n-Butylpiperidine-2-carboxylic Acid 2,6-Dimethylanilide Hydrochloride; Sensorcaine
Original China
CAS 14252-80-3
EINECS 241-917-8
Molecular formula C18H31ClN2O2
Molecular Weight 342.9
Brand name NJBNSteroid
Delivery time within 24 hours upon receipt of payment
Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity 99%
Package Discreet and Hidden package according to specific requirement
Appearance White powder
Certification SGS, ISO 9001, KOSHER
Payment Terms Western Union, Money Gram , T/T, Bitcoin
Minimum Order Quantity 10g
Price Negotiable
Usage It is used for pain control

2. Description of Bupivacaine hydrochloride

Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to make it last longer. It typically begins working within 15 minutes and lasts for 2 to 8 hours.

Bupivacaine hydrochloride injection, USP is available in sterile isotonic solution for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. Solution of Bupivacaine hydrochloride injection, USP may be autoclaved. Solution is clear and colorless.

Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.

Bupivacaine hydrochloride injection, USP - Sterile isotonic solution containing sodium chloride. The pH of the solution is adjusted to between 4 and 6.5 with sodium hydroxide or hydrochloric acid.

3. Clinical Application of Bupivacaine hydrochloride

Bupivacaine is indicated for local infiltration, peripheral nerve block, sympathetic nerve block, and epidural and caudal blocks. It is sometimes used in combination with epinephrine to prevent systemic absorption and extend the duration of action. The 0.75% (most concentrated) formulation is used in retrobulbar block. It is the most commonly used local anesthetic in epidural anesthesia during labor, as well as in postoperative pain management.

It is prescribed for caudal, epidural, peripheral, or sympathetic anesthetic block.
A local anaesthetic of the amide type used in eye surgery. It is used in 0.25-0.75% solution. It is often mixed with lidocaine hydrochloride. Its action starts after about 5 minutes and lasts for about 10 hours.

4.Technical Testing Sheet

Product Desdription: BUPIVACAINE HYDROCHLORIDE(HCL)
Standard: USP32
Test Items Standard Test Results
Character White crystalline powder Conforms
Identification IR
UV
The aqueous layer responds to the tests for Chloride
Conforms

Conforms
Conforms
PH 4.5-6.0 5.8
Heavy metal Not more than 0.001% Conforms
Water 4.0%-6.0% 5.5%
Residue on ignition Not more than 0.1% 0.04%
Limit of residual solvents Not more than 2% Conforms
Chromatographic purity Total impurity: < 2.0%
Individual impurity: < 0.5%
Conforms
Conforms
Assay 98.5%-101.5% 99.50%
Conclusion All analytical methods and results conform to the requirement of USP32.

5. Local anesthetics

Benzocaine CAS: 94-09-7
Benzocaine hydrochloride CAS: 23239-88-5
Tetracaine hydrochloride CAS: 136-47-0
Procaine CAS: 59-46-1
Lidocaine CAS: 137-58-6
Dibucaine hydrochloride CAS: 61-12-1
Prilocaine CAS: 721-50-6
Propitocaine hydrochloride CAS: 1786-81-8
Proparacaine hydrochloride CAS: 5875-06-9
Lidocaine hydrochloride CAS: 73-78-9
Articaine hydrochloride CAS: 23964-57-0
Levobupivacaine hydrochloride CAS: 27262-48-2
Ropivacaine hydrochloride CAS: 132112-35-7
Bupivacaine CAS: 2180-92-9
Bupivacaine hydrochloride CAS: 14252-80-3
Tetracaine CAS: 94-24-6
Pramoxine Hydrochloride CAS: 637-58-1
Procaine HCl CAS: 51-05-8

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