High purity 99.5% Local Anesthetic Drugs Anodyne CAS 136-47-0 Tetracaine HCl / Tetracaine Hydrochloride For Mucosa Anti-pain

Basic information

Product Name:	Tetracaine hydrochloride
Synonyms:	L AND OCAIN HYDROCHLORIDE; INTERCAIN HYDROCHLORIDE; MEETHOBALM HYDROCHLORIDE; 2-(DIMETHYLAMINO)ETHYL 4-(N-BUTYLAMINO)BENZOATE HYDROCHLORIDE; 2-DIMETHYLAMINOETHYL ESTER OFP-BUTYLAMINOBENZOIC ACID HYDROCHLORIDE; 4-(N-BUTYLAMINO)BENZOIC ACID 2-(DIMETHYLAMINO) ETHYL ESTER HYDROCHLORIDE; 4-[BUTYLAMINO]BENZOIC ACID-2- [DIMETHYLAMINO]ETHYL ESTER HYDROCHLORIDE; 4-BUTYLAMINOBENZOIC ACID DIMETHYLAMINOETHYL ESTER HCL
CAS:	136-47-0
MF:	C15H25ClN2O2
MW:	300.82
EINECS:	205-248-5
Product Categories:	API intermediates; Sodium channel; Amines; Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals; Pharmaceutical intermediate; PONTOCAINE; Local anesthetic
Usage	A local anesthetic used topically in opthalmology.
Chemical	White Solid

Tetracaine hydrochloride---Description

• Tetracaine hydrochlorideis synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

Tetracaine hydrochloride---Application

• Tetracaine hydrochloride(INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

• Tetracaine hydrochloride, In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

Specification

COA:

Test Items	Specification	Test Results
Appearance	Fine, white, crystalline, odorless powder	confirm
Identification	ABC in Pass	confirm
Solubility	Very soluble in water, soluble in Alcohol; insoluble in Ether and Benzene	confirm
USP Reference standards	USP Tetracaine Hydrochloride RS. USP Endotoxin RS.	Confirm
Melting point	145~150 degree	146.0~147.5 degree
Chromatographic purity	In Pass	confirm
Related substance	Not more than the reference solution 0.05%	confirm
Heavy metals	≤10ppm	confirm
PH	4.5-6.5	5.8
Residue on ignition	≤0.10%	0.05%
Loss on Drying	≤ 0.5%	0.19%
Assay	98.0 -101.0%	100.1%
Conclusion	Confirms USP 32

Tetracaine hydrochloride---Usages:

• Tetracaine hydrochloride, Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

• Tetracaine hydrochloride, In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. 2. Tetracaine is an allosteric blocker of channel function.

• Tetracaine hydrochloride, At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

Packaging & Delivery

1. Professional team for package and shipment.
2. Fast and discreet shipment could be arranged for customs pass Guaranteed.
3. Tracking code 24hours for customs pass guaranteed.
4. After-sale service: Problems would be solved for you immediately.

Why Us?

• Professional raw powder factory in China, all powders are factory directly supplying. Have over 10 years' honour.

• Our products are exported to many countrie such as Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and so on, over 100kgs each month.

• Most of powders are in stock. Chargeable samples are available. Products could be shipped out within 24hours.

• Our products and services will focus on the largest customer demand. We hold the greatest enthusiasm and sincerity in cooperation with each customer.

• A discount would be given when you place a large order.

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