| Purity: | 98 |
|---|---|
| Model Number: | C22H29FO5 |
| Brand Name: | NJ STERIOD |
| Usage: | Animal Pharmaceuticals |
| Grade Standard: | Medicine Grade |
| Type: | Auxiliaries and Other Medicinal Chemicals |
| Place of Origin: | China (Mainland) |
| EINECS No.: | C22H29FO5 |
| CAS No.: | 50-02-2 |
| 50-02-2: | 1USD(changeable) |
Quick Details
Specifications
Product Description
Detailed Product Description
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Storage: : |
Keep Out Of The Sun. | Packing: : | 25kg/foil Bag |
| Delivery Ways: : | EMS, HKEMS, TNT, DHL, FedEX, UPS Etc. | Shipment Time: : | Within 8 Hours After Confirmation Of Your Payment |
| Other Service: : | We Confirm 99% Clearance, 100% Resending. | Export Markets: : | Global |
Antiallergic Cortical Hormone Dexamethaslo Anti Inflammatory Supplements Without Side Effect CAS 50-02-2
1 . Application of Dexamethaslo:
Dexamethaslo wide range of applications, the role of strong, significantly, is commonly used corticosteroids, in the rescue of allergic diseases, shock, and other severe acute endocrine crisis have played a key role, is indispensable clinical drugs. Dexamethasone anti-inflammatory effects and control skin allergy stronger than prednisone, its anti-inflammatory activity equivalent to 0.75mg 5mg prednisone, skin allergies better. For status asthmaticus critical situation of the disease, it may be a good short-term high-dose intravenous dexamethasone effects, intravenous infusion every 5 ~ 20mg, 4 ~ 6h can be repeated dosing, reduction after 48 ~ 72h, 5 ~ 7 days withdrawal. Patients with cerebral edema due to various reasons can be given for the first time 10mg intravenous injection. Every 4 to 6 hours after intramuscular injection of 2 ~ 4mg, generally can be alleviated within 24h, 48 ~ 72h reductions, 7 days withdrawal.
2 . Basic Overview :
Dexamethaslo
CAS: 50-02-2
EINECS: 200-003-9
Quality standard: Bp/USP/EP
MF: C22H29FO5
MW: 392.46
Density: 1.32g/cm3
Melting point: 255-264o C
Boiling point: 568.2o C at 760 mmHg
Flash point: 297.5o C
Refractive index: 76 ° (C=1, Dioxane)
Vapour pressure: 2.81E-15mmHg at 25o C
Solubility: 10 mg/100 mL (25o C)
Usage: Dexamethaslo and other sugar cortical hormone, has anti-inflammatory, anti-endotoxin, suppress the immune, resistance to shock and to enhance the pharmacological effects, such as the stress response, so it is widely applied in the treatment of many diseases in all the subjects, such as autoimmune diseases, allergy, inflammation, asthma and skin and eye disease.
3 . Description :
Dexamethaslo is a synthetic corticosteroid with approximately 25 times the anti-inflammatory potency of naturally occurring cortisol. The IUPAC Name of it is (8S, 9R, 10S, 11S, 13S, 14S, 16R, 17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl6,7,8,11,12,14,15, octahydrocyclopenta[a]phenanthren-3-one. Dexamethaslo commonly is used in both small- and large-animal veterinary medicine. It may be given by injection, inhalation orally or topically. Preparations for topical use may include other active ingredients such as antibiotics, antifungals or miticides.
4 . Related Products:
Dexamethaslo Specifications:
|
Test Items |
Specification |
Test Results |
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|
Appearance |
White oralmost white, crystalline powder |
Conform |
|
|
Solubility |
Freely soluble in water, practically insoluble or very slightly soluble in alcohol and in methylene chloride. |
Conform |
|
|
Identification |
A |
The UV absorption spectrum of the sample shows an absorption maximum at 276nm. The specific absorbance at the Maximum is55 to 64. |
Conform |
|
B |
Infraed absorption spectrophotometry. |
Conform |
|
|
C |
Chromatogram obtained with test solution (b) is similar in position color & size to the principal spot in the chromatogram obtained with the reference solution. |
Conform |
|
|
D |
An orange-red color develop in methylene chloride layer. |
Conform |
|
|
E |
It geves reaction (a) of sulphates. |
Conform |
|
|
Appearance of solution |
Solution S is clear and not more intensely coloured than reference solution in BY6. |
Conform |
|
|
Optical rotation |
-0.10° to +0.10°determined on solution S. |
+0.01° |
|
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Acidity or alkalinity |
NMT 0.4ml of 0.01M HCL is required to change the color of the indicator to red. |
Conform |
|
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Related substances |
Impurity J ≤0.20% |
Conform |
|
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Any other impurity ≤0.30% |
Conform |
||
|
Total impurity ≤1.0% |
Conform |
||
|
Boron |
≤50ppm |
Conform |
|
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Sulphated ash |
≤0.10% |
0.06% |
|
|
Loss on drying |
≤0.5% |
0.30% |
|
|
Assay(on dried basis) |
98.0~101.0% |
98.8% |
|
|
Conclusion |
The test results above BP2009 |
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