Natural White Lyophilized Powder 75921-69-6 Melanotan-1 for Muscle Buidling


Quick Detail:

Product Name	Melanotan-1
Alias	Proviron
CAS NO	75921-69-6
MF	C78H111N21O19
MW	1646.85
Mol File	75921-69-6. Mol
Assay	99% min
Melting point	208 °C
Appearance	white to off-white crystalline powder
Storage	20°C
Grade	Pharmaceutical Grade
Delivery time	Within 24 hours upon receipt of payment
Shipping	EMS, DHL, TNT, FedEx, UPS
Synonyms	[NLE4, D-PHE]ALPHA-MELANOCYTE STIMULATING HORMONE; (NLE4, D-PHE7)-ALPHA-MSH; [NLE4, D-PHE7]-ALPHA-MSH, AMIDE; [NLE4, D-PHE7]-ALPHA-MELANOCYTE-STIMULATING HORMONE; [NLE4, DPHE7] ALPHA-MELANOCYTE STIMULATING HORMONE, AMIDE; NDP-MSHAC-SER-TYR-SER-NLE-GLU-HIS-D-PHE-ARG-TRP-GLY-LYS-PRO-VAL-NH2; NDP-MSH; MELANOTAN I

Product Description:

1. Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

2. Melanotan 1 - a peptide that causes sunburn and has a function to strengthen erections and increase libido. The drug is a synthetic analog of the peptide melanocortin, which determines the color of the skin and sunburn. Peptide helps to achieve the desired shade of tan in a very short period of time - from 15 to 20 days. It is also possible to accelerate pigmentation, visiting the solarium or sunbathing on the sun in Europe.

3. MT 1 prepares the skin to tan, significantly reducing the risk of sunburn, as well as preventing the development of melanoma. If the skin is burned under the influence of sunlight, then peel off melanotanom chances are reduced. Synthetic Melanotan was developed in the US as a means of protection against cancerous skin lesions, because the peptide does not transmit ultraviolet rays and has a protective effect of protecting the skin. Modification of melanocortin (which is subject to very rapid decay when introduced into the body) is called Melanotan-2. This peptide was approximately 1000 times more powerful than its natural counterpart and patented called Melanotan-1. The peptide Melanotan passed 3 stages of clinical trials, in which proved high efficiency and quality of the drug.

Applications:

Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). CAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.

1)Enhances the tan

2)Further accelerates the pigmentation of the solarium or sun exposure

3)Amplifies erection (within 2 hours after the first injection administration

4)It has a property to suppress appetite

5)Also works as an aphrodisiac

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