• Model NO. : The effect of antipyretic analgesic
• CAS: Reduce The Acute Pains
• Purity: 99%
• MW: 179.22
• Delivery Time: 2-3 Work Days
• Shipping Express: Eub, Hkems, EMS, DHL, TNT, FedEx, Aramex, UPS.
• Specification: 99%
• HS Code: 3001

• Phenacetin-Acetate: Analgesic & Antipyretic
• Packaging Details: Foil Bag, or as Your Demand
• Molecular Formula: C10h13no2
• Synonyms: Kafa; Soma; Dasin; Fenia; Malex; Tacol; Viden; Xaril; Anap
• Payment Method: Western Union, T/T, Bitcoins, Moneygram, Paypal
• Trademark: SGS ISO9001
• Origin: HK China of Hksjg

99% Phenacetin-Acetate Pharmaceutical Intermediates Used as Antipyretic-analgesic

keywords:
natural pain killers, local anesthetic drugs

Quick Details:
English name: PHENACETINUM-Acetate or PHENACETIN-Acetate
Content: 99%
Molecular formula: C10H13NO2
Molecular weight: 179.2158
Category: raw material medicine, antipyretic and analgesic drugs raw materials.
Characteristics: This product is white, there is a flash of scale like crystal or white crystalline powder, no
smell, taste bitter. This product is dissolved in ethanol or chloroform, slightly soluble in boiling water
Soluble in water.
MOQ: 10G
Manufacturers: HKSJG
Shipping express: EUB, HKEMS, EMS, DHL, TNT, Fedex, Aramex, UPS, etc.
Payment method:

Detailed Descriptions of Phenacertin: Using for : reliving wound pains:
Section 1st.
It is also called acetophenetidin. Having glossy leaflets or scales-like crystals that have no odor or taste.
Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in
ether, soluble in ethanol, chloroform. It is formed through the etherification, reduction and Acetylation
reaction of pchloronitrobenzene. As chloroacetanilide antipyretic and analgesic agent. Suitable for fever, headache, neuralgia and other drugs as a compound agent.

Section 2nd.
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin,
low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic
effect. Because the enzyme inhibitor make phenacetin-Acetate not be converted into paracetamol, still showed
obvious antipyretic effect, thus the antipyretic effect after the product line not converrt to paracetamol. The
mild phenacetin-Acetate analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid
coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.

Setion 3rd.
Phenacetin-Acetate is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887 until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized into paracetamol, which replaced it in some over-the-counter medications following the ban on phenacetin-Acetate.

Phenacetin-Acetate Property
mp : 133-136 °C(lit. )
bp : 132 °C / 4mmHg
storage temp. : 2-8°C
form : white powder
Water Solubility : 0.076 g/100 mL
Sensitive : Hygroscopic
Merck : 14,7204
BRN : 1869238
Stability : Stable. Incompatible with strong oxidizing agents, strong acids.


Detailed Applications of Phenacetin-Acetate : for Analgestic & Antipyretic :

Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin-Acetate is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin-Acetate are listed as known human carcinogens.

Phenacetin-Acetate was widely used until the third quarter of the twentieth century, often in the form of an "A. P. C. " or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent's APC in Australia. However the U. S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin-Acetate in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)). It was also banned in India. As a result some branded, previously phenacetin-Acetate based preparations continued to be sold, but with the phenacetin-Acetate replaced by safer alternatives. A popular brand of phenacetin-Acetate was Roche's Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin-Acetate . Paracetamol is a metabolite of phenacetin-Acetate with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin-Acetate's carcinogenicity.
Phenacetin-Acetate is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.
Due to low cost phenacetin-Acetate is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.